Cargando…

Alzheimer Disease Classification through Transfer Learning Approach

Alzheimer’s disease (AD) is a slow neurological disorder that destroys the thought process, and consciousness, of a human. It directly affects the development of mental ability and neurocognitive functionality. The number of patients with Alzheimer’s disease is increasing day by day, especially in o...

Descripción completa

Detalles Bibliográficos
Autores principales: Raza, Noman, Naseer, Asma, Tamoor, Maria, Zafar, Kashif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955379/
https://www.ncbi.nlm.nih.gov/pubmed/36832292
http://dx.doi.org/10.3390/diagnostics13040801
_version_ 1784894331860025344
author Raza, Noman
Naseer, Asma
Tamoor, Maria
Zafar, Kashif
author_facet Raza, Noman
Naseer, Asma
Tamoor, Maria
Zafar, Kashif
author_sort Raza, Noman
collection PubMed
description Alzheimer’s disease (AD) is a slow neurological disorder that destroys the thought process, and consciousness, of a human. It directly affects the development of mental ability and neurocognitive functionality. The number of patients with Alzheimer’s disease is increasing day by day, especially in old aged people, who are above 60 years of age, and, gradually, it becomes cause of their death. In this research, we discuss the segmentation and classification of the Magnetic resonance imaging (MRI) of Alzheimer’s disease, through the concept of transfer learning and customizing of the convolutional neural network (CNN) by specifically using images that are segmented by the Gray Matter (GM) of the brain. Instead of training and computing the proposed model accuracy from the start, we used a pre-trained deep learning model as our base model, and, after that, transfer learning was applied. The accuracy of the proposed model was tested over a different number of epochs, 10, 25, and 50. The overall accuracy of the proposed model was 97.84%.
format Online
Article
Text
id pubmed-9955379
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-99553792023-02-25 Alzheimer Disease Classification through Transfer Learning Approach Raza, Noman Naseer, Asma Tamoor, Maria Zafar, Kashif Diagnostics (Basel) Article Alzheimer’s disease (AD) is a slow neurological disorder that destroys the thought process, and consciousness, of a human. It directly affects the development of mental ability and neurocognitive functionality. The number of patients with Alzheimer’s disease is increasing day by day, especially in old aged people, who are above 60 years of age, and, gradually, it becomes cause of their death. In this research, we discuss the segmentation and classification of the Magnetic resonance imaging (MRI) of Alzheimer’s disease, through the concept of transfer learning and customizing of the convolutional neural network (CNN) by specifically using images that are segmented by the Gray Matter (GM) of the brain. Instead of training and computing the proposed model accuracy from the start, we used a pre-trained deep learning model as our base model, and, after that, transfer learning was applied. The accuracy of the proposed model was tested over a different number of epochs, 10, 25, and 50. The overall accuracy of the proposed model was 97.84%. MDPI 2023-02-20 /pmc/articles/PMC9955379/ /pubmed/36832292 http://dx.doi.org/10.3390/diagnostics13040801 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Raza, Noman
Naseer, Asma
Tamoor, Maria
Zafar, Kashif
Alzheimer Disease Classification through Transfer Learning Approach
title Alzheimer Disease Classification through Transfer Learning Approach
title_full Alzheimer Disease Classification through Transfer Learning Approach
title_fullStr Alzheimer Disease Classification through Transfer Learning Approach
title_full_unstemmed Alzheimer Disease Classification through Transfer Learning Approach
title_short Alzheimer Disease Classification through Transfer Learning Approach
title_sort alzheimer disease classification through transfer learning approach
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955379/
https://www.ncbi.nlm.nih.gov/pubmed/36832292
http://dx.doi.org/10.3390/diagnostics13040801
work_keys_str_mv AT razanoman alzheimerdiseaseclassificationthroughtransferlearningapproach
AT naseerasma alzheimerdiseaseclassificationthroughtransferlearningapproach
AT tamoormaria alzheimerdiseaseclassificationthroughtransferlearningapproach
AT zafarkashif alzheimerdiseaseclassificationthroughtransferlearningapproach