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Alzheimer Disease Classification through Transfer Learning Approach
Alzheimer’s disease (AD) is a slow neurological disorder that destroys the thought process, and consciousness, of a human. It directly affects the development of mental ability and neurocognitive functionality. The number of patients with Alzheimer’s disease is increasing day by day, especially in o...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955379/ https://www.ncbi.nlm.nih.gov/pubmed/36832292 http://dx.doi.org/10.3390/diagnostics13040801 |
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author | Raza, Noman Naseer, Asma Tamoor, Maria Zafar, Kashif |
author_facet | Raza, Noman Naseer, Asma Tamoor, Maria Zafar, Kashif |
author_sort | Raza, Noman |
collection | PubMed |
description | Alzheimer’s disease (AD) is a slow neurological disorder that destroys the thought process, and consciousness, of a human. It directly affects the development of mental ability and neurocognitive functionality. The number of patients with Alzheimer’s disease is increasing day by day, especially in old aged people, who are above 60 years of age, and, gradually, it becomes cause of their death. In this research, we discuss the segmentation and classification of the Magnetic resonance imaging (MRI) of Alzheimer’s disease, through the concept of transfer learning and customizing of the convolutional neural network (CNN) by specifically using images that are segmented by the Gray Matter (GM) of the brain. Instead of training and computing the proposed model accuracy from the start, we used a pre-trained deep learning model as our base model, and, after that, transfer learning was applied. The accuracy of the proposed model was tested over a different number of epochs, 10, 25, and 50. The overall accuracy of the proposed model was 97.84%. |
format | Online Article Text |
id | pubmed-9955379 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99553792023-02-25 Alzheimer Disease Classification through Transfer Learning Approach Raza, Noman Naseer, Asma Tamoor, Maria Zafar, Kashif Diagnostics (Basel) Article Alzheimer’s disease (AD) is a slow neurological disorder that destroys the thought process, and consciousness, of a human. It directly affects the development of mental ability and neurocognitive functionality. The number of patients with Alzheimer’s disease is increasing day by day, especially in old aged people, who are above 60 years of age, and, gradually, it becomes cause of their death. In this research, we discuss the segmentation and classification of the Magnetic resonance imaging (MRI) of Alzheimer’s disease, through the concept of transfer learning and customizing of the convolutional neural network (CNN) by specifically using images that are segmented by the Gray Matter (GM) of the brain. Instead of training and computing the proposed model accuracy from the start, we used a pre-trained deep learning model as our base model, and, after that, transfer learning was applied. The accuracy of the proposed model was tested over a different number of epochs, 10, 25, and 50. The overall accuracy of the proposed model was 97.84%. MDPI 2023-02-20 /pmc/articles/PMC9955379/ /pubmed/36832292 http://dx.doi.org/10.3390/diagnostics13040801 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Raza, Noman Naseer, Asma Tamoor, Maria Zafar, Kashif Alzheimer Disease Classification through Transfer Learning Approach |
title | Alzheimer Disease Classification through Transfer Learning Approach |
title_full | Alzheimer Disease Classification through Transfer Learning Approach |
title_fullStr | Alzheimer Disease Classification through Transfer Learning Approach |
title_full_unstemmed | Alzheimer Disease Classification through Transfer Learning Approach |
title_short | Alzheimer Disease Classification through Transfer Learning Approach |
title_sort | alzheimer disease classification through transfer learning approach |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955379/ https://www.ncbi.nlm.nih.gov/pubmed/36832292 http://dx.doi.org/10.3390/diagnostics13040801 |
work_keys_str_mv | AT razanoman alzheimerdiseaseclassificationthroughtransferlearningapproach AT naseerasma alzheimerdiseaseclassificationthroughtransferlearningapproach AT tamoormaria alzheimerdiseaseclassificationthroughtransferlearningapproach AT zafarkashif alzheimerdiseaseclassificationthroughtransferlearningapproach |