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Analysis of Cause-of-Death Mortality in Children and Young Adults with Diabetes: A Nationwide 10-Year Follow-Up Cohort Study

We examined the associations of clinical characteristics and cause-of-death patterns with mortality in children and young adults (<30 years) with diabetes. We analyzed a nationwide cohort sample from the KNHIS database using propensity score matching from a sample of 1 million people from 2002 to...

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Autores principales: Choi, Iee-Ho, Yeom, Sang-Woo, Kim, Sun-Young, You, Jihye, Kim, Jong-Seung, Kim, Minsun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955437/
https://www.ncbi.nlm.nih.gov/pubmed/36832487
http://dx.doi.org/10.3390/children10020358
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author Choi, Iee-Ho
Yeom, Sang-Woo
Kim, Sun-Young
You, Jihye
Kim, Jong-Seung
Kim, Minsun
author_facet Choi, Iee-Ho
Yeom, Sang-Woo
Kim, Sun-Young
You, Jihye
Kim, Jong-Seung
Kim, Minsun
author_sort Choi, Iee-Ho
collection PubMed
description We examined the associations of clinical characteristics and cause-of-death patterns with mortality in children and young adults (<30 years) with diabetes. We analyzed a nationwide cohort sample from the KNHIS database using propensity score matching from a sample of 1 million people from 2002 to 2013. There were 10,006 individuals in the diabetes mellitus (DM) group and 10,006 in the control (no DM) group. The numbers of deaths were 77 in the DM group and 20 in the control group. The deaths of patients in the DM Group were 3.74 (95% confidence interval (CI) = 2.25–6.21) times higher than in the control group. Type 1 DM, type 2 DM and unspecified DM were 4.52 (95% CI = 1.89–10.82) times, 3.25 (95% CI = 1.95–5.43) times and 10.20 (95% CI = 5.24–20.18) times higher, respectively. Mental disorders were 2.08 times higher in the risk of death (95% CI = 1.27–3.40). Mortality rates have increased in children and young adults with diabetes alone. Therefore, in the future, it is necessary to identify the cause of the increased mortality rate among young diabetic people and select vulnerable groups among them so that early prevention can be achieved.
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spelling pubmed-99554372023-02-25 Analysis of Cause-of-Death Mortality in Children and Young Adults with Diabetes: A Nationwide 10-Year Follow-Up Cohort Study Choi, Iee-Ho Yeom, Sang-Woo Kim, Sun-Young You, Jihye Kim, Jong-Seung Kim, Minsun Children (Basel) Article We examined the associations of clinical characteristics and cause-of-death patterns with mortality in children and young adults (<30 years) with diabetes. We analyzed a nationwide cohort sample from the KNHIS database using propensity score matching from a sample of 1 million people from 2002 to 2013. There were 10,006 individuals in the diabetes mellitus (DM) group and 10,006 in the control (no DM) group. The numbers of deaths were 77 in the DM group and 20 in the control group. The deaths of patients in the DM Group were 3.74 (95% confidence interval (CI) = 2.25–6.21) times higher than in the control group. Type 1 DM, type 2 DM and unspecified DM were 4.52 (95% CI = 1.89–10.82) times, 3.25 (95% CI = 1.95–5.43) times and 10.20 (95% CI = 5.24–20.18) times higher, respectively. Mental disorders were 2.08 times higher in the risk of death (95% CI = 1.27–3.40). Mortality rates have increased in children and young adults with diabetes alone. Therefore, in the future, it is necessary to identify the cause of the increased mortality rate among young diabetic people and select vulnerable groups among them so that early prevention can be achieved. MDPI 2023-02-10 /pmc/articles/PMC9955437/ /pubmed/36832487 http://dx.doi.org/10.3390/children10020358 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Choi, Iee-Ho
Yeom, Sang-Woo
Kim, Sun-Young
You, Jihye
Kim, Jong-Seung
Kim, Minsun
Analysis of Cause-of-Death Mortality in Children and Young Adults with Diabetes: A Nationwide 10-Year Follow-Up Cohort Study
title Analysis of Cause-of-Death Mortality in Children and Young Adults with Diabetes: A Nationwide 10-Year Follow-Up Cohort Study
title_full Analysis of Cause-of-Death Mortality in Children and Young Adults with Diabetes: A Nationwide 10-Year Follow-Up Cohort Study
title_fullStr Analysis of Cause-of-Death Mortality in Children and Young Adults with Diabetes: A Nationwide 10-Year Follow-Up Cohort Study
title_full_unstemmed Analysis of Cause-of-Death Mortality in Children and Young Adults with Diabetes: A Nationwide 10-Year Follow-Up Cohort Study
title_short Analysis of Cause-of-Death Mortality in Children and Young Adults with Diabetes: A Nationwide 10-Year Follow-Up Cohort Study
title_sort analysis of cause-of-death mortality in children and young adults with diabetes: a nationwide 10-year follow-up cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955437/
https://www.ncbi.nlm.nih.gov/pubmed/36832487
http://dx.doi.org/10.3390/children10020358
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