NEAT1–SOD2 Axis Confers Sorafenib and Lenvatinib Resistance by Activating AKT in Liver Cancer Cell Lines

This study investigated the effects of a long noncoding RNA, nuclear paraspeckle assembly transcript 1 (NEAT1) variant 1 (NEAT1v1) on drug resistance in liver cancer cell lines. NEAT1 knockdown activated mitogen-activated protein kinase (MAPK) signaling pathways, including MAPK kinase (MEK)/extracel...

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Detalles Bibliográficos
Autores principales: Tsuchiya, Hiroyuki, Shinonaga, Ririko, Sakaguchi, Hiromi, Kitagawa, Yutaka, Yoshida, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955465/
https://www.ncbi.nlm.nih.gov/pubmed/36826016
http://dx.doi.org/10.3390/cimb45020071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955465/
https://www.ncbi.nlm.nih.gov/pubmed/36826016
http://dx.doi.org/10.3390/cimb45020071

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