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Long-term interplay between COVID-19 and chronic kidney disease

PURPOSE: The COVID-19 pandemic may have an impact on the long-term kidney function of survivors. The clinical relevance is not clear. METHODS: This review summarises the currently published data. RESULTS: There is a bidirectional relationship between chronic kidney disease and COVID-19 disease. Chro...

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Autores principales: Schiffl, Helmut, Lang, Susanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955527/
https://www.ncbi.nlm.nih.gov/pubmed/36828919
http://dx.doi.org/10.1007/s11255-023-03528-x
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author Schiffl, Helmut
Lang, Susanne M.
author_facet Schiffl, Helmut
Lang, Susanne M.
author_sort Schiffl, Helmut
collection PubMed
description PURPOSE: The COVID-19 pandemic may have an impact on the long-term kidney function of survivors. The clinical relevance is not clear. METHODS: This review summarises the currently published data. RESULTS: There is a bidirectional relationship between chronic kidney disease and COVID-19 disease. Chronic kidney diseases due to primary kidney disease or chronic conditions affecting kidneys increase the susceptibility to COVID-19 infection, the risks for progression and critical COVID-19 disease (with acute or acute-on-chronic kidney damage), and death. Patients who have survived COVID-19 face an increased risk of worse kidney outcomes in the post-acute phase of the disease. Of clinical significance, COVID-19 may predispose surviving patients to chronic kidney disease, independently of clinically apparent acute kidney injury (AKI). The increased risk of post-acute renal dysfunction of COVID-19 patients can be graded according to the severity of the acute infection (non-hospitalised, hospitalised or ICU patients). The burden of chronic kidney disease developing after COVID-19 is currently unknown. CONCLUSION: Post-acute COVID-19 care should include close attention to kidney function. Future prospective large-scale studies are needed with long and complete follow-up periods, assessing kidney function using novel markers of kidney function/damage, urinalysis and biopsy studies.
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spelling pubmed-99555272023-02-28 Long-term interplay between COVID-19 and chronic kidney disease Schiffl, Helmut Lang, Susanne M. Int Urol Nephrol Nephrology - Review PURPOSE: The COVID-19 pandemic may have an impact on the long-term kidney function of survivors. The clinical relevance is not clear. METHODS: This review summarises the currently published data. RESULTS: There is a bidirectional relationship between chronic kidney disease and COVID-19 disease. Chronic kidney diseases due to primary kidney disease or chronic conditions affecting kidneys increase the susceptibility to COVID-19 infection, the risks for progression and critical COVID-19 disease (with acute or acute-on-chronic kidney damage), and death. Patients who have survived COVID-19 face an increased risk of worse kidney outcomes in the post-acute phase of the disease. Of clinical significance, COVID-19 may predispose surviving patients to chronic kidney disease, independently of clinically apparent acute kidney injury (AKI). The increased risk of post-acute renal dysfunction of COVID-19 patients can be graded according to the severity of the acute infection (non-hospitalised, hospitalised or ICU patients). The burden of chronic kidney disease developing after COVID-19 is currently unknown. CONCLUSION: Post-acute COVID-19 care should include close attention to kidney function. Future prospective large-scale studies are needed with long and complete follow-up periods, assessing kidney function using novel markers of kidney function/damage, urinalysis and biopsy studies. Springer Netherlands 2023-02-24 /pmc/articles/PMC9955527/ /pubmed/36828919 http://dx.doi.org/10.1007/s11255-023-03528-x Text en © The Author(s), under exclusive licence to Springer Nature B.V. 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Nephrology - Review
Schiffl, Helmut
Lang, Susanne M.
Long-term interplay between COVID-19 and chronic kidney disease
title Long-term interplay between COVID-19 and chronic kidney disease
title_full Long-term interplay between COVID-19 and chronic kidney disease
title_fullStr Long-term interplay between COVID-19 and chronic kidney disease
title_full_unstemmed Long-term interplay between COVID-19 and chronic kidney disease
title_short Long-term interplay between COVID-19 and chronic kidney disease
title_sort long-term interplay between covid-19 and chronic kidney disease
topic Nephrology - Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955527/
https://www.ncbi.nlm.nih.gov/pubmed/36828919
http://dx.doi.org/10.1007/s11255-023-03528-x
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