Cargando…

Cardiopulmonary Ultrasound Patterns of Transient Acute Respiratory Distress of the Newborn: A Retrospective Pilot Study

Acute transient respiratory distress in the first hours of life is usually defined as transient tachypnea of the newborn (TTN). TTN is a respiratory self-limiting disorder consequent to delayed lung fluid clearance at birth. While TTN is the most common etiology of respiratory distress near term, it...

Descripción completa

Detalles Bibliográficos
Autores principales: Pierro, Maria, Chioma, Roberto, Benincasa, Consuelo, Gagliardi, Giacomo, Amabili, Lorenzo, Lelli, Francesca, De Luca, Giovanni, Storti, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955778/
https://www.ncbi.nlm.nih.gov/pubmed/36832418
http://dx.doi.org/10.3390/children10020289
_version_ 1784894430330748928
author Pierro, Maria
Chioma, Roberto
Benincasa, Consuelo
Gagliardi, Giacomo
Amabili, Lorenzo
Lelli, Francesca
De Luca, Giovanni
Storti, Enrico
author_facet Pierro, Maria
Chioma, Roberto
Benincasa, Consuelo
Gagliardi, Giacomo
Amabili, Lorenzo
Lelli, Francesca
De Luca, Giovanni
Storti, Enrico
author_sort Pierro, Maria
collection PubMed
description Acute transient respiratory distress in the first hours of life is usually defined as transient tachypnea of the newborn (TTN). TTN is a respiratory self-limiting disorder consequent to delayed lung fluid clearance at birth. While TTN is the most common etiology of respiratory distress near term, its pathogenesis and diagnostic criteria are not well-defined. Lung ultrasound and targeted neonatal echocardiography are increasingly being used to assess critically ill infants, although their combined use to improve diagnostic precision in neonatal intensive care units has not yet been described. This retrospective pilot analysis aimed to identify possible cardiopulmonary ultrasound (CPUS) patterns in term and late preterm infants suffering from transient respiratory distress and requiring non-invasive respiratory support. After retrospectively revising CPUS images, we found seven potential sonographic phenotypes of acute neonatal respiratory distress. Up to 50% of the patients presented with signs of increased pulmonary vascular resistance, suggesting that those patients may be diagnosed with mild forms of persistent pulmonary hypertension of the newborn. Approximately 80% of the infants with a history of meconium-stained amniotic fluid displayed irregular atelectasis, indicating that they may have suffered from mild meconium aspiration syndrome. CPUS evaluation may improve accuracy in the approach to the infants presenting with transient acute respiratory distress, supporting communication with the parents and carrying important epidemiological consequences.
format Online
Article
Text
id pubmed-9955778
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-99557782023-02-25 Cardiopulmonary Ultrasound Patterns of Transient Acute Respiratory Distress of the Newborn: A Retrospective Pilot Study Pierro, Maria Chioma, Roberto Benincasa, Consuelo Gagliardi, Giacomo Amabili, Lorenzo Lelli, Francesca De Luca, Giovanni Storti, Enrico Children (Basel) Article Acute transient respiratory distress in the first hours of life is usually defined as transient tachypnea of the newborn (TTN). TTN is a respiratory self-limiting disorder consequent to delayed lung fluid clearance at birth. While TTN is the most common etiology of respiratory distress near term, its pathogenesis and diagnostic criteria are not well-defined. Lung ultrasound and targeted neonatal echocardiography are increasingly being used to assess critically ill infants, although their combined use to improve diagnostic precision in neonatal intensive care units has not yet been described. This retrospective pilot analysis aimed to identify possible cardiopulmonary ultrasound (CPUS) patterns in term and late preterm infants suffering from transient respiratory distress and requiring non-invasive respiratory support. After retrospectively revising CPUS images, we found seven potential sonographic phenotypes of acute neonatal respiratory distress. Up to 50% of the patients presented with signs of increased pulmonary vascular resistance, suggesting that those patients may be diagnosed with mild forms of persistent pulmonary hypertension of the newborn. Approximately 80% of the infants with a history of meconium-stained amniotic fluid displayed irregular atelectasis, indicating that they may have suffered from mild meconium aspiration syndrome. CPUS evaluation may improve accuracy in the approach to the infants presenting with transient acute respiratory distress, supporting communication with the parents and carrying important epidemiological consequences. MDPI 2023-02-02 /pmc/articles/PMC9955778/ /pubmed/36832418 http://dx.doi.org/10.3390/children10020289 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pierro, Maria
Chioma, Roberto
Benincasa, Consuelo
Gagliardi, Giacomo
Amabili, Lorenzo
Lelli, Francesca
De Luca, Giovanni
Storti, Enrico
Cardiopulmonary Ultrasound Patterns of Transient Acute Respiratory Distress of the Newborn: A Retrospective Pilot Study
title Cardiopulmonary Ultrasound Patterns of Transient Acute Respiratory Distress of the Newborn: A Retrospective Pilot Study
title_full Cardiopulmonary Ultrasound Patterns of Transient Acute Respiratory Distress of the Newborn: A Retrospective Pilot Study
title_fullStr Cardiopulmonary Ultrasound Patterns of Transient Acute Respiratory Distress of the Newborn: A Retrospective Pilot Study
title_full_unstemmed Cardiopulmonary Ultrasound Patterns of Transient Acute Respiratory Distress of the Newborn: A Retrospective Pilot Study
title_short Cardiopulmonary Ultrasound Patterns of Transient Acute Respiratory Distress of the Newborn: A Retrospective Pilot Study
title_sort cardiopulmonary ultrasound patterns of transient acute respiratory distress of the newborn: a retrospective pilot study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955778/
https://www.ncbi.nlm.nih.gov/pubmed/36832418
http://dx.doi.org/10.3390/children10020289
work_keys_str_mv AT pierromaria cardiopulmonaryultrasoundpatternsoftransientacuterespiratorydistressofthenewbornaretrospectivepilotstudy
AT chiomaroberto cardiopulmonaryultrasoundpatternsoftransientacuterespiratorydistressofthenewbornaretrospectivepilotstudy
AT benincasaconsuelo cardiopulmonaryultrasoundpatternsoftransientacuterespiratorydistressofthenewbornaretrospectivepilotstudy
AT gagliardigiacomo cardiopulmonaryultrasoundpatternsoftransientacuterespiratorydistressofthenewbornaretrospectivepilotstudy
AT amabililorenzo cardiopulmonaryultrasoundpatternsoftransientacuterespiratorydistressofthenewbornaretrospectivepilotstudy
AT lellifrancesca cardiopulmonaryultrasoundpatternsoftransientacuterespiratorydistressofthenewbornaretrospectivepilotstudy
AT delucagiovanni cardiopulmonaryultrasoundpatternsoftransientacuterespiratorydistressofthenewbornaretrospectivepilotstudy
AT stortienrico cardiopulmonaryultrasoundpatternsoftransientacuterespiratorydistressofthenewbornaretrospectivepilotstudy