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Development and validation of prediction models for the discharge destination of elderly patients with aspiration pneumonia

BACKGROUND: Discharge planning enhances the safe and timely transfer of inpatients between facilities. Predicting the discharge destination of inpatients with aspiration pneumonia is important for discharge planning. We aimed to develop and validate prediction models for the discharge destination of...

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Autores principales: Hirota, Yoshito, Shin, Jung-ho, Sasaki, Noriko, Kunisawa, Susumu, Fushimi, Kiyohide, Imanaka, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955922/
https://www.ncbi.nlm.nih.gov/pubmed/36827320
http://dx.doi.org/10.1371/journal.pone.0282272
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author Hirota, Yoshito
Shin, Jung-ho
Sasaki, Noriko
Kunisawa, Susumu
Fushimi, Kiyohide
Imanaka, Yuichi
author_facet Hirota, Yoshito
Shin, Jung-ho
Sasaki, Noriko
Kunisawa, Susumu
Fushimi, Kiyohide
Imanaka, Yuichi
author_sort Hirota, Yoshito
collection PubMed
description BACKGROUND: Discharge planning enhances the safe and timely transfer of inpatients between facilities. Predicting the discharge destination of inpatients with aspiration pneumonia is important for discharge planning. We aimed to develop and validate prediction models for the discharge destination of elderly patients with aspiration pneumonia. METHODS: Using a nationwide inpatient database, we identified aspiration pneumonia cases for patients aged ≥65 years who had been admitted to hospital from their home or from a nursing home between April 2020 and March 2021. We divided the cases into derivation and validation cohorts according to the location of the admitting hospital. We developed two prediction models by dividing the cases based on the patient’s place of residence prior to admission, one model to predict the home discharge of cases admitted from home and the other to predict the home or to a nursing home discharge of cases admitted from a nursing home. The models were internally validated with bootstrapping and internal-externally validated using a validation cohort. Nomograms that could be used easily in clinical practice were also created. RESULTS: The derivation cohort included 19,746 cases admitted from home and 14,359 cases admitted from a nursing home. Of the former, 10,760 (54.5%) cases were discharged home; from the latter, 7,071 (49.2%) were discharged to either home or a nursing home. The validation cohort included 6,262 cases admitted from home and 6,352 cases admitted from a nursing home. In the internal-external validation, the C-statistics of the final model for the cases admitted from home and the cases admitted from a nursing home were 0.71 and 0.67, respectively. CONCLUSIONS: We developed and validated new prediction models for the discharge of elderly patients with aspiration pneumonia either to home or to a nursing home. Our models and nomograms could facilitate the early implementation of discharge planning.
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spelling pubmed-99559222023-02-25 Development and validation of prediction models for the discharge destination of elderly patients with aspiration pneumonia Hirota, Yoshito Shin, Jung-ho Sasaki, Noriko Kunisawa, Susumu Fushimi, Kiyohide Imanaka, Yuichi PLoS One Research Article BACKGROUND: Discharge planning enhances the safe and timely transfer of inpatients between facilities. Predicting the discharge destination of inpatients with aspiration pneumonia is important for discharge planning. We aimed to develop and validate prediction models for the discharge destination of elderly patients with aspiration pneumonia. METHODS: Using a nationwide inpatient database, we identified aspiration pneumonia cases for patients aged ≥65 years who had been admitted to hospital from their home or from a nursing home between April 2020 and March 2021. We divided the cases into derivation and validation cohorts according to the location of the admitting hospital. We developed two prediction models by dividing the cases based on the patient’s place of residence prior to admission, one model to predict the home discharge of cases admitted from home and the other to predict the home or to a nursing home discharge of cases admitted from a nursing home. The models were internally validated with bootstrapping and internal-externally validated using a validation cohort. Nomograms that could be used easily in clinical practice were also created. RESULTS: The derivation cohort included 19,746 cases admitted from home and 14,359 cases admitted from a nursing home. Of the former, 10,760 (54.5%) cases were discharged home; from the latter, 7,071 (49.2%) were discharged to either home or a nursing home. The validation cohort included 6,262 cases admitted from home and 6,352 cases admitted from a nursing home. In the internal-external validation, the C-statistics of the final model for the cases admitted from home and the cases admitted from a nursing home were 0.71 and 0.67, respectively. CONCLUSIONS: We developed and validated new prediction models for the discharge of elderly patients with aspiration pneumonia either to home or to a nursing home. Our models and nomograms could facilitate the early implementation of discharge planning. Public Library of Science 2023-02-24 /pmc/articles/PMC9955922/ /pubmed/36827320 http://dx.doi.org/10.1371/journal.pone.0282272 Text en © 2023 Hirota et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Hirota, Yoshito
Shin, Jung-ho
Sasaki, Noriko
Kunisawa, Susumu
Fushimi, Kiyohide
Imanaka, Yuichi
Development and validation of prediction models for the discharge destination of elderly patients with aspiration pneumonia
title Development and validation of prediction models for the discharge destination of elderly patients with aspiration pneumonia
title_full Development and validation of prediction models for the discharge destination of elderly patients with aspiration pneumonia
title_fullStr Development and validation of prediction models for the discharge destination of elderly patients with aspiration pneumonia
title_full_unstemmed Development and validation of prediction models for the discharge destination of elderly patients with aspiration pneumonia
title_short Development and validation of prediction models for the discharge destination of elderly patients with aspiration pneumonia
title_sort development and validation of prediction models for the discharge destination of elderly patients with aspiration pneumonia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955922/
https://www.ncbi.nlm.nih.gov/pubmed/36827320
http://dx.doi.org/10.1371/journal.pone.0282272
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