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A Well-Posed Fractional Order Cholera Model with Saturated Incidence Rate

A fractional-order cholera model in the Caputo sense is constructed. The model is an extension of the Susceptible–Infected–Recovered (SIR) epidemic model. The transmission dynamics of the disease are studied by incorporating the saturated incidence rate into the model. This is particularly important...

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Detalles Bibliográficos
Autores principales: Baba, Isa Abdullahi, Humphries, Usa Wannasingha, Rihan, Fathalla A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955935/
https://www.ncbi.nlm.nih.gov/pubmed/36832726
http://dx.doi.org/10.3390/e25020360
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author Baba, Isa Abdullahi
Humphries, Usa Wannasingha
Rihan, Fathalla A.
author_facet Baba, Isa Abdullahi
Humphries, Usa Wannasingha
Rihan, Fathalla A.
author_sort Baba, Isa Abdullahi
collection PubMed
description A fractional-order cholera model in the Caputo sense is constructed. The model is an extension of the Susceptible–Infected–Recovered (SIR) epidemic model. The transmission dynamics of the disease are studied by incorporating the saturated incidence rate into the model. This is particularly important since assuming that the increase in incidence for a large number of infected individualsis equivalent to a small number of infected individualsdoes not make much sense. The positivity, boundedness, existence, and uniqueness of the solution of the model are also studied. Equilibrium solutions are computed, and their stability analyses are shown to depend on a threshold quantity, the basic reproduction ratio ([Formula: see text]). It is clearly shown that if [Formula: see text] the disease-free equilibrium is locally asymptotically stable, whereas if [Formula: see text] , the endemic equilibrium exists and is locally asymptotically stable. Numerical simulations are carried out to support the analytic results and to show the significance of the fractional order from the biological point of view. Furthermore, the significance of awareness is studied in the numerical section.
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spelling pubmed-99559352023-02-25 A Well-Posed Fractional Order Cholera Model with Saturated Incidence Rate Baba, Isa Abdullahi Humphries, Usa Wannasingha Rihan, Fathalla A. Entropy (Basel) Article A fractional-order cholera model in the Caputo sense is constructed. The model is an extension of the Susceptible–Infected–Recovered (SIR) epidemic model. The transmission dynamics of the disease are studied by incorporating the saturated incidence rate into the model. This is particularly important since assuming that the increase in incidence for a large number of infected individualsis equivalent to a small number of infected individualsdoes not make much sense. The positivity, boundedness, existence, and uniqueness of the solution of the model are also studied. Equilibrium solutions are computed, and their stability analyses are shown to depend on a threshold quantity, the basic reproduction ratio ([Formula: see text]). It is clearly shown that if [Formula: see text] the disease-free equilibrium is locally asymptotically stable, whereas if [Formula: see text] , the endemic equilibrium exists and is locally asymptotically stable. Numerical simulations are carried out to support the analytic results and to show the significance of the fractional order from the biological point of view. Furthermore, the significance of awareness is studied in the numerical section. MDPI 2023-02-15 /pmc/articles/PMC9955935/ /pubmed/36832726 http://dx.doi.org/10.3390/e25020360 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Baba, Isa Abdullahi
Humphries, Usa Wannasingha
Rihan, Fathalla A.
A Well-Posed Fractional Order Cholera Model with Saturated Incidence Rate
title A Well-Posed Fractional Order Cholera Model with Saturated Incidence Rate
title_full A Well-Posed Fractional Order Cholera Model with Saturated Incidence Rate
title_fullStr A Well-Posed Fractional Order Cholera Model with Saturated Incidence Rate
title_full_unstemmed A Well-Posed Fractional Order Cholera Model with Saturated Incidence Rate
title_short A Well-Posed Fractional Order Cholera Model with Saturated Incidence Rate
title_sort well-posed fractional order cholera model with saturated incidence rate
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955935/
https://www.ncbi.nlm.nih.gov/pubmed/36832726
http://dx.doi.org/10.3390/e25020360
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