Droplet digital PCR-based testing for donor-derived cell-free DNA in transplanted patients as noninvasive marker of allograft health: Methodological aspects

In solid organ transplantation, donor-derived cell-free DNA (dd-cfDNA) is a promising universal noninvasive biomarker for allograft health, where high levels of dd-cfDNA indicate organ damage. Using Droplet Digital PCR (ddPCR), we aimed to develop an assay setup for monitoring organ health. We aimed...

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Detalles Bibliográficos
Autores principales: Clausen, Frederik Banch, Jørgensen, Kristine Mathilde Clara Lund, Wardil, Lasse Witt, Nielsen, Leif Kofoed, Krog, Grethe Risum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955980/
https://www.ncbi.nlm.nih.gov/pubmed/36827438
http://dx.doi.org/10.1371/journal.pone.0282332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955980/
https://www.ncbi.nlm.nih.gov/pubmed/36827438
http://dx.doi.org/10.1371/journal.pone.0282332

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