Cargando…

Postnatal Outcomes of Fetuses with Prenatal Diagnosis of 6–9.9 mm Pyelectasis

Pyelectasis, also known as renal pelvic dilatation or hydronephrosis, is frequently found on fetal ultrasound. This study correlated prenatally-detected, moderate pyelectasis with postnatal outcomes. This retrospective, observational study was conducted at a tertiary medical center in Israel. The st...

Descripción completa

Detalles Bibliográficos
Autores principales: Farladansky-Gershnabel, Sivan, Gluska, Hadar, Meyer, Segev, Sharon-Weiner, Maya, Schreiber, Hanoch, Arnon, Shmuel, Markovitch, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955995/
https://www.ncbi.nlm.nih.gov/pubmed/36832536
http://dx.doi.org/10.3390/children10020407
_version_ 1784894484014694400
author Farladansky-Gershnabel, Sivan
Gluska, Hadar
Meyer, Segev
Sharon-Weiner, Maya
Schreiber, Hanoch
Arnon, Shmuel
Markovitch, Ofer
author_facet Farladansky-Gershnabel, Sivan
Gluska, Hadar
Meyer, Segev
Sharon-Weiner, Maya
Schreiber, Hanoch
Arnon, Shmuel
Markovitch, Ofer
author_sort Farladansky-Gershnabel, Sivan
collection PubMed
description Pyelectasis, also known as renal pelvic dilatation or hydronephrosis, is frequently found on fetal ultrasound. This study correlated prenatally-detected, moderate pyelectasis with postnatal outcomes. This retrospective, observational study was conducted at a tertiary medical center in Israel. The study group consisted of 54 fetuses with prenatal diagnosis of pyelectasis on ultrasound scan during the second trimester, defined as anteroposterior renal pelvic diameter (APRPD) 6–9.9 mm. Long-term postnatal outcomes and renal-related sequelae were obtained using medical records and telephone-based questionnaires. The control group included 98 cases with APRPD < 6 mm. Results indicate that fetal pyelectasis 6–9.9 mm was more frequent among males (68.5%) than females (51%, p = 0.034). We did not find significant correlations between 6–9.9 mm pyelectasis and other anomalies or chromosomal/genetic disorders. Pyelectasis resolved during the pregnancy in 15/54 (27.8%) cases. There was no change in 17/54 (31.5%) and 22/54 (40.7%) progressed to hydronephrosis Among the study group, 25/54 (46.3%) were diagnosed with neonatal hydronephrosis. There were more cases of renal reflux or renal obstruction in the study group compared to the control group 8/54 (14.8%) vs. 1/98 (1.0%), respectively; p = 0.002. In conclusion, most cases of 6–9.9 mm pyelectasis remained stable or resolved spontaneously during pregnancy. There was a higher rate of postnatal renal reflux and renal obstruction in this group; however, most did not require surgical intervention.
format Online
Article
Text
id pubmed-9955995
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-99559952023-02-25 Postnatal Outcomes of Fetuses with Prenatal Diagnosis of 6–9.9 mm Pyelectasis Farladansky-Gershnabel, Sivan Gluska, Hadar Meyer, Segev Sharon-Weiner, Maya Schreiber, Hanoch Arnon, Shmuel Markovitch, Ofer Children (Basel) Article Pyelectasis, also known as renal pelvic dilatation or hydronephrosis, is frequently found on fetal ultrasound. This study correlated prenatally-detected, moderate pyelectasis with postnatal outcomes. This retrospective, observational study was conducted at a tertiary medical center in Israel. The study group consisted of 54 fetuses with prenatal diagnosis of pyelectasis on ultrasound scan during the second trimester, defined as anteroposterior renal pelvic diameter (APRPD) 6–9.9 mm. Long-term postnatal outcomes and renal-related sequelae were obtained using medical records and telephone-based questionnaires. The control group included 98 cases with APRPD < 6 mm. Results indicate that fetal pyelectasis 6–9.9 mm was more frequent among males (68.5%) than females (51%, p = 0.034). We did not find significant correlations between 6–9.9 mm pyelectasis and other anomalies or chromosomal/genetic disorders. Pyelectasis resolved during the pregnancy in 15/54 (27.8%) cases. There was no change in 17/54 (31.5%) and 22/54 (40.7%) progressed to hydronephrosis Among the study group, 25/54 (46.3%) were diagnosed with neonatal hydronephrosis. There were more cases of renal reflux or renal obstruction in the study group compared to the control group 8/54 (14.8%) vs. 1/98 (1.0%), respectively; p = 0.002. In conclusion, most cases of 6–9.9 mm pyelectasis remained stable or resolved spontaneously during pregnancy. There was a higher rate of postnatal renal reflux and renal obstruction in this group; however, most did not require surgical intervention. MDPI 2023-02-19 /pmc/articles/PMC9955995/ /pubmed/36832536 http://dx.doi.org/10.3390/children10020407 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Farladansky-Gershnabel, Sivan
Gluska, Hadar
Meyer, Segev
Sharon-Weiner, Maya
Schreiber, Hanoch
Arnon, Shmuel
Markovitch, Ofer
Postnatal Outcomes of Fetuses with Prenatal Diagnosis of 6–9.9 mm Pyelectasis
title Postnatal Outcomes of Fetuses with Prenatal Diagnosis of 6–9.9 mm Pyelectasis
title_full Postnatal Outcomes of Fetuses with Prenatal Diagnosis of 6–9.9 mm Pyelectasis
title_fullStr Postnatal Outcomes of Fetuses with Prenatal Diagnosis of 6–9.9 mm Pyelectasis
title_full_unstemmed Postnatal Outcomes of Fetuses with Prenatal Diagnosis of 6–9.9 mm Pyelectasis
title_short Postnatal Outcomes of Fetuses with Prenatal Diagnosis of 6–9.9 mm Pyelectasis
title_sort postnatal outcomes of fetuses with prenatal diagnosis of 6–9.9 mm pyelectasis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9955995/
https://www.ncbi.nlm.nih.gov/pubmed/36832536
http://dx.doi.org/10.3390/children10020407
work_keys_str_mv AT farladanskygershnabelsivan postnataloutcomesoffetuseswithprenataldiagnosisof699mmpyelectasis
AT gluskahadar postnataloutcomesoffetuseswithprenataldiagnosisof699mmpyelectasis
AT meyersegev postnataloutcomesoffetuseswithprenataldiagnosisof699mmpyelectasis
AT sharonweinermaya postnataloutcomesoffetuseswithprenataldiagnosisof699mmpyelectasis
AT schreiberhanoch postnataloutcomesoffetuseswithprenataldiagnosisof699mmpyelectasis
AT arnonshmuel postnataloutcomesoffetuseswithprenataldiagnosisof699mmpyelectasis
AT markovitchofer postnataloutcomesoffetuseswithprenataldiagnosisof699mmpyelectasis