Transient binding sites at the surface of haloalkane dehalogenase LinB as locations for fine-tuning enzymatic activity

The haloalkane dehalogenase LinB is a well-known enzyme that contains buried active site and is used for many modelling studies. Using classical molecular dynamics simulations of enzymes and substrates, we searched for transient binding sites on the surface of the LinB protein by calculating maps of...

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Detalles Bibliográficos
Autores principales: Raczyńska, Agata, Kapica, Patryk, Papaj, Katarzyna, Stańczak, Agnieszka, Shyntum, Divine, Spychalska, Patrycja, Byczek-Wyrostek, Anna, Góra, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956002/
https://www.ncbi.nlm.nih.gov/pubmed/36827335
http://dx.doi.org/10.1371/journal.pone.0280776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956002/
https://www.ncbi.nlm.nih.gov/pubmed/36827335
http://dx.doi.org/10.1371/journal.pone.0280776

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