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Laser Cleaning Improves Stem Cell Adhesion on the Dental Implant Surface during Peri-Implantitis Treatment
Dental implant therapy is a well-accepted treatment modality. Despite good predictability and success in the early stages, the risk of postplacement inflammation in the long-term periods remains an urgent problem. Surgical access and decontamination with chemical and mechanical methods are more effe...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956030/ https://www.ncbi.nlm.nih.gov/pubmed/36826175 http://dx.doi.org/10.3390/dj11020030 |
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author | Furtsev, Taras V. Koshmanova, Anastasia A. Zeer, Galina M. Nikolaeva, Elena D. Lapin, Ivan N. Zamay, Tatiana N. Kichkailo, Anna S. |
author_facet | Furtsev, Taras V. Koshmanova, Anastasia A. Zeer, Galina M. Nikolaeva, Elena D. Lapin, Ivan N. Zamay, Tatiana N. Kichkailo, Anna S. |
author_sort | Furtsev, Taras V. |
collection | PubMed |
description | Dental implant therapy is a well-accepted treatment modality. Despite good predictability and success in the early stages, the risk of postplacement inflammation in the long-term periods remains an urgent problem. Surgical access and decontamination with chemical and mechanical methods are more effective than antibiotic therapy. The search for the optimal and predictable way for peri-implantitis treatment remains relevant. Here, we evaluated four cleaning methods for their ability to preserve the implant’s surface for adequate mesenchymal stem cell adhesion and differentiation. Implants isolated after peri-implantitis were subjected to cleaning with diamond bur; Ti-Ni alloy brush, air-flow, or Er,Cr:YSGG laser and cocultured with mice MSC for five weeks. Dental bur and titanium brushes destroyed the implants’ surfaces and prevented MSC attachment. Air-flow and laser minimally affected the dental implant surface microroughness, which was initially designed for good cell adhesion and bone remodeling and to provide full microbial decontamination. Anodized with titanium dioxide and sandblasted with aluminum oxide, acid-etched implants appeared to be better for laser treatment. In implants sandblasted with aluminum oxide, an acid-etched surface better preserves its topology when treated with the air-flow. These cleaning methods minimally affect the implant’s surface, so it maintains the capability to absorb osteogenic cells for further division and differentiation. |
format | Online Article Text |
id | pubmed-9956030 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99560302023-02-25 Laser Cleaning Improves Stem Cell Adhesion on the Dental Implant Surface during Peri-Implantitis Treatment Furtsev, Taras V. Koshmanova, Anastasia A. Zeer, Galina M. Nikolaeva, Elena D. Lapin, Ivan N. Zamay, Tatiana N. Kichkailo, Anna S. Dent J (Basel) Article Dental implant therapy is a well-accepted treatment modality. Despite good predictability and success in the early stages, the risk of postplacement inflammation in the long-term periods remains an urgent problem. Surgical access and decontamination with chemical and mechanical methods are more effective than antibiotic therapy. The search for the optimal and predictable way for peri-implantitis treatment remains relevant. Here, we evaluated four cleaning methods for their ability to preserve the implant’s surface for adequate mesenchymal stem cell adhesion and differentiation. Implants isolated after peri-implantitis were subjected to cleaning with diamond bur; Ti-Ni alloy brush, air-flow, or Er,Cr:YSGG laser and cocultured with mice MSC for five weeks. Dental bur and titanium brushes destroyed the implants’ surfaces and prevented MSC attachment. Air-flow and laser minimally affected the dental implant surface microroughness, which was initially designed for good cell adhesion and bone remodeling and to provide full microbial decontamination. Anodized with titanium dioxide and sandblasted with aluminum oxide, acid-etched implants appeared to be better for laser treatment. In implants sandblasted with aluminum oxide, an acid-etched surface better preserves its topology when treated with the air-flow. These cleaning methods minimally affect the implant’s surface, so it maintains the capability to absorb osteogenic cells for further division and differentiation. MDPI 2023-01-20 /pmc/articles/PMC9956030/ /pubmed/36826175 http://dx.doi.org/10.3390/dj11020030 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Furtsev, Taras V. Koshmanova, Anastasia A. Zeer, Galina M. Nikolaeva, Elena D. Lapin, Ivan N. Zamay, Tatiana N. Kichkailo, Anna S. Laser Cleaning Improves Stem Cell Adhesion on the Dental Implant Surface during Peri-Implantitis Treatment |
title | Laser Cleaning Improves Stem Cell Adhesion on the Dental Implant Surface during Peri-Implantitis Treatment |
title_full | Laser Cleaning Improves Stem Cell Adhesion on the Dental Implant Surface during Peri-Implantitis Treatment |
title_fullStr | Laser Cleaning Improves Stem Cell Adhesion on the Dental Implant Surface during Peri-Implantitis Treatment |
title_full_unstemmed | Laser Cleaning Improves Stem Cell Adhesion on the Dental Implant Surface during Peri-Implantitis Treatment |
title_short | Laser Cleaning Improves Stem Cell Adhesion on the Dental Implant Surface during Peri-Implantitis Treatment |
title_sort | laser cleaning improves stem cell adhesion on the dental implant surface during peri-implantitis treatment |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956030/ https://www.ncbi.nlm.nih.gov/pubmed/36826175 http://dx.doi.org/10.3390/dj11020030 |
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