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Swelling and Viscoelastic Properties of Cellulose-Based Hydrogels Prepared by Free Radical Polymerization of Dimethylaminoethyl Methacrylate in Cellulose Solution
The grafting of a stimuli-responsive polymer (poly(dimethylaminoethyl methacrylate)) onto cellulose was achieved by performing free radical polymerization of a vinyl/divinyl monomer in cellulose solution. The grafting and crosslinking efficiency in the material have been increased by subsequent irra...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956197/ https://www.ncbi.nlm.nih.gov/pubmed/36826264 http://dx.doi.org/10.3390/gels9020094 |
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author | Blažic, Roko Marušić, Katarina Vidović, Elvira |
author_facet | Blažic, Roko Marušić, Katarina Vidović, Elvira |
author_sort | Blažic, Roko |
collection | PubMed |
description | The grafting of a stimuli-responsive polymer (poly(dimethylaminoethyl methacrylate)) onto cellulose was achieved by performing free radical polymerization of a vinyl/divinyl monomer in cellulose solution. The grafting and crosslinking efficiency in the material have been increased by subsequent irradiation of the samples with ionizing radiation (doses of 10, 30, or 100 kGy). The relative amount of poly(dimethylaminoethyl methacrylate) in the prepared hydrogels was determined by infrared spectroscopy. The swelling behavior of the hydrogels was studied thoroughly, including microgelation extent, equilibrium swelling, and reswelling degree, as well as the dependence on the gelation procedure. The dynamic viscoelastic behavior of prepared hydrogels was also studied. The tan δ values indicate a solid-like behavior while the obtained hydrogels have a complex modulus in the range of 14–39 kPa, which is suitable for hydrogels used in biomedical applications. In addition, the incorporation of Ag particles and the adsorption of Fe(3+) ions were tested to evaluate the additional functionalities of the prepared hydrogels. It was found that the introduction of PDMAEMA to the hydrogels enhanced their ability to synthesize Ag particles and absorb Fe(3+) ions, providing a platform for the potential preparation of hydrogels for the treatment of wounds. |
format | Online Article Text |
id | pubmed-9956197 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99561972023-02-25 Swelling and Viscoelastic Properties of Cellulose-Based Hydrogels Prepared by Free Radical Polymerization of Dimethylaminoethyl Methacrylate in Cellulose Solution Blažic, Roko Marušić, Katarina Vidović, Elvira Gels Article The grafting of a stimuli-responsive polymer (poly(dimethylaminoethyl methacrylate)) onto cellulose was achieved by performing free radical polymerization of a vinyl/divinyl monomer in cellulose solution. The grafting and crosslinking efficiency in the material have been increased by subsequent irradiation of the samples with ionizing radiation (doses of 10, 30, or 100 kGy). The relative amount of poly(dimethylaminoethyl methacrylate) in the prepared hydrogels was determined by infrared spectroscopy. The swelling behavior of the hydrogels was studied thoroughly, including microgelation extent, equilibrium swelling, and reswelling degree, as well as the dependence on the gelation procedure. The dynamic viscoelastic behavior of prepared hydrogels was also studied. The tan δ values indicate a solid-like behavior while the obtained hydrogels have a complex modulus in the range of 14–39 kPa, which is suitable for hydrogels used in biomedical applications. In addition, the incorporation of Ag particles and the adsorption of Fe(3+) ions were tested to evaluate the additional functionalities of the prepared hydrogels. It was found that the introduction of PDMAEMA to the hydrogels enhanced their ability to synthesize Ag particles and absorb Fe(3+) ions, providing a platform for the potential preparation of hydrogels for the treatment of wounds. MDPI 2023-01-21 /pmc/articles/PMC9956197/ /pubmed/36826264 http://dx.doi.org/10.3390/gels9020094 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Blažic, Roko Marušić, Katarina Vidović, Elvira Swelling and Viscoelastic Properties of Cellulose-Based Hydrogels Prepared by Free Radical Polymerization of Dimethylaminoethyl Methacrylate in Cellulose Solution |
title | Swelling and Viscoelastic Properties of Cellulose-Based Hydrogels Prepared by Free Radical Polymerization of Dimethylaminoethyl Methacrylate in Cellulose Solution |
title_full | Swelling and Viscoelastic Properties of Cellulose-Based Hydrogels Prepared by Free Radical Polymerization of Dimethylaminoethyl Methacrylate in Cellulose Solution |
title_fullStr | Swelling and Viscoelastic Properties of Cellulose-Based Hydrogels Prepared by Free Radical Polymerization of Dimethylaminoethyl Methacrylate in Cellulose Solution |
title_full_unstemmed | Swelling and Viscoelastic Properties of Cellulose-Based Hydrogels Prepared by Free Radical Polymerization of Dimethylaminoethyl Methacrylate in Cellulose Solution |
title_short | Swelling and Viscoelastic Properties of Cellulose-Based Hydrogels Prepared by Free Radical Polymerization of Dimethylaminoethyl Methacrylate in Cellulose Solution |
title_sort | swelling and viscoelastic properties of cellulose-based hydrogels prepared by free radical polymerization of dimethylaminoethyl methacrylate in cellulose solution |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956197/ https://www.ncbi.nlm.nih.gov/pubmed/36826264 http://dx.doi.org/10.3390/gels9020094 |
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