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TCF7L1 Regulates LGR5 Expression in Colorectal Cancer Cells

Mutations in components of the Wnt/β-catenin signaling pathway drive colorectal cancer (CRC), in part, by deregulating expression of genes controlled by the T-cell factor (TCF) family of transcription factors. TCFs contain a conserved DNA binding domain that mediates association with TCF binding ele...

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Detalles Bibliográficos
Autores principales: King, Carli M., Marx, Olivia M., Ding, Wei, Koltun, Walter A., Yochum, Gregory S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956233/
https://www.ncbi.nlm.nih.gov/pubmed/36833408
http://dx.doi.org/10.3390/genes14020481