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Dynamic Evolution of NLR Genes in Dalbergioids
Dalbergioid is a large group within the family Fabaceae that consists of diverse plant species distributed in distinct biogeographic realms. Here, we have performed a comprehensive study to understand the evolution of the nucleotide-binding leucine-rich repeats (NLRs) gene family in Dalbergioids. Th...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956324/ https://www.ncbi.nlm.nih.gov/pubmed/36833304 http://dx.doi.org/10.3390/genes14020377 |
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author | Rani, Shamiza Zahra, Ramlah Bakar, Abu Rizwan, Muhammad Sultan, Abu-Bakar Zain, Muhammad Mehmood, Amna Danial, Muhammad Shakoor, Sidra Saleem, Fozia Serfraz, Ali Rehman, Hafiz Mamoon Khan, Rao Sohail Ahmad Serfraz, Saad AlKahtani, Saad |
author_facet | Rani, Shamiza Zahra, Ramlah Bakar, Abu Rizwan, Muhammad Sultan, Abu-Bakar Zain, Muhammad Mehmood, Amna Danial, Muhammad Shakoor, Sidra Saleem, Fozia Serfraz, Ali Rehman, Hafiz Mamoon Khan, Rao Sohail Ahmad Serfraz, Saad AlKahtani, Saad |
author_sort | Rani, Shamiza |
collection | PubMed |
description | Dalbergioid is a large group within the family Fabaceae that consists of diverse plant species distributed in distinct biogeographic realms. Here, we have performed a comprehensive study to understand the evolution of the nucleotide-binding leucine-rich repeats (NLRs) gene family in Dalbergioids. The evolution of gene families in this group is affected by a common whole genome duplication that occurred approximately 58 million years ago, followed by diploidization that often leads to contraction. Our study suggests that since diploidization, the NLRome of all groups of Dalbergioids is expanding in a clade-specific manner with fewer exceptions. Phylogenetic analysis and classification of NLRs revealed that they belong to seven subgroups. Specific subgroups have expanded in a species-specific manner, leading to divergent evolution. Among the Dalbergia clade, the expansion of NLRome in six species of the genus Dalbergia was observed, with the exception of Dalbergia odorifera, where a recent contraction of NLRome occurred. Similarly, members of the Pterocarpus clade genus Arachis revealed a large-scale expansion in the diploid species. In addition, the asymmetric expansion of NLRome was observed in wild and domesticated tetraploids after recent duplications in the genus Arachis. Our analysis strongly suggests that whole genome duplication followed by tandem duplication after divergence from a common ancestor of Dalbergioids is the major cause of NLRome expansion. To the best of our knowledge, this is the first ever study to provide insight toward the evolution of NLR genes in this important tribe. In addition, accurate identification and characterization of NLR genes is a substantial contribution to the repertoire of resistances among members of the Dalbergioids species. |
format | Online Article Text |
id | pubmed-9956324 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99563242023-02-25 Dynamic Evolution of NLR Genes in Dalbergioids Rani, Shamiza Zahra, Ramlah Bakar, Abu Rizwan, Muhammad Sultan, Abu-Bakar Zain, Muhammad Mehmood, Amna Danial, Muhammad Shakoor, Sidra Saleem, Fozia Serfraz, Ali Rehman, Hafiz Mamoon Khan, Rao Sohail Ahmad Serfraz, Saad AlKahtani, Saad Genes (Basel) Article Dalbergioid is a large group within the family Fabaceae that consists of diverse plant species distributed in distinct biogeographic realms. Here, we have performed a comprehensive study to understand the evolution of the nucleotide-binding leucine-rich repeats (NLRs) gene family in Dalbergioids. The evolution of gene families in this group is affected by a common whole genome duplication that occurred approximately 58 million years ago, followed by diploidization that often leads to contraction. Our study suggests that since diploidization, the NLRome of all groups of Dalbergioids is expanding in a clade-specific manner with fewer exceptions. Phylogenetic analysis and classification of NLRs revealed that they belong to seven subgroups. Specific subgroups have expanded in a species-specific manner, leading to divergent evolution. Among the Dalbergia clade, the expansion of NLRome in six species of the genus Dalbergia was observed, with the exception of Dalbergia odorifera, where a recent contraction of NLRome occurred. Similarly, members of the Pterocarpus clade genus Arachis revealed a large-scale expansion in the diploid species. In addition, the asymmetric expansion of NLRome was observed in wild and domesticated tetraploids after recent duplications in the genus Arachis. Our analysis strongly suggests that whole genome duplication followed by tandem duplication after divergence from a common ancestor of Dalbergioids is the major cause of NLRome expansion. To the best of our knowledge, this is the first ever study to provide insight toward the evolution of NLR genes in this important tribe. In addition, accurate identification and characterization of NLR genes is a substantial contribution to the repertoire of resistances among members of the Dalbergioids species. MDPI 2023-01-31 /pmc/articles/PMC9956324/ /pubmed/36833304 http://dx.doi.org/10.3390/genes14020377 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Rani, Shamiza Zahra, Ramlah Bakar, Abu Rizwan, Muhammad Sultan, Abu-Bakar Zain, Muhammad Mehmood, Amna Danial, Muhammad Shakoor, Sidra Saleem, Fozia Serfraz, Ali Rehman, Hafiz Mamoon Khan, Rao Sohail Ahmad Serfraz, Saad AlKahtani, Saad Dynamic Evolution of NLR Genes in Dalbergioids |
title | Dynamic Evolution of NLR Genes in Dalbergioids |
title_full | Dynamic Evolution of NLR Genes in Dalbergioids |
title_fullStr | Dynamic Evolution of NLR Genes in Dalbergioids |
title_full_unstemmed | Dynamic Evolution of NLR Genes in Dalbergioids |
title_short | Dynamic Evolution of NLR Genes in Dalbergioids |
title_sort | dynamic evolution of nlr genes in dalbergioids |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956324/ https://www.ncbi.nlm.nih.gov/pubmed/36833304 http://dx.doi.org/10.3390/genes14020377 |
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