Cargando…

Whole Exome Sequencing Study Suggests an Impact of FANCA, CDH1 and VEGFA Genes on Diffuse Gastric Cancer Development

Gastric cancer (GC) is one of the most common cancer types in the world with a high mortality rate. Hereditary predisposition for GC is not fully elucidated so far. The aim of this study was identification of possible new candidate genes, associated with the increased risk of gastric cancer developm...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nurgalieva, Alfiia, Galliamova, Lilia, Ekomasova, Natalia, Yankina, Maria, Sakaeva, Dina, Valiev, Ruslan, Prokofyeva, Darya, Dzhaubermezov, Murat, Fedorova, Yuliya, Khusnutdinov, Shamil, Khusnutdinova, Elza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956399/ https://www.ncbi.nlm.nih.gov/pubmed/36833207 http://dx.doi.org/10.3390/genes14020280

Ejemplares similares

Genetic Polymorphisms of Cytochromes P450 in Finno-Permic Populations of Russia
por: Dzhaubermezov, Murat, et al.
Publicado: (2022)

Targeted next-generation sequencing of 21 candidate genes in hereditary ovarian cancer patients from the Republic of Bashkortostan
por: Prokofyeva, D. S., et al.
Publicado: (2023)

Structural Variability, Expression Profile, and Pharmacogenetic Properties of TMPRSS2 Gene as a Potential Target for COVID-19 Therapy
por: Zarubin, Aleksei, et al.
Publicado: (2020)

Coregulation of FANCA and BRCA1 in human cells
por: Haitjema, Anneke, et al.
Publicado: (2014)

Investigation of FANCA gene in Fanconi anaemia patients in Iran
por: Saffar Moghadam, Ali Akbar, et al.
Publicado: (2016)

Rare variants in FANCA induce premature ovarian insufficiency
por: Yang, Xi, et al.
Publicado: (2019)

FANCA Polymorphism Is Associated with the Rate of Proliferation in Uterine Leiomyoma in Korea
por: Ha, Eunyoung, et al.
Publicado: (2020)

FANCA Gene Mutations in North African Fanconi Anemia Patients
por: Ben Haj Ali, Abir, et al.
Publicado: (2021)

Fanca deficiency is associated with alterations in osteoclastogenesis that are rescued by TNFα
por: Oppezzo, Alessia, et al.
Publicado: (2023)

A Splice Site Variant of CDK12 and Breast Cancer in Three Eurasian Populations
por: Bogdanova, Natalia V., et al.
Publicado: (2019)

Identification of Three Novel Mutations in the FANCA, FANCC, and ITGA2B Genes by Whole Exome Sequencing
por: Negahdari, Samira, et al.
Publicado: (2020)

Treatment of FANCA Cells with Resveratrol and N-Acetylcysteine: A Comparative Study
por: Columbaro, Marta, et al.
Publicado: (2014)

Hypomorphic FANCA mutations correlate with mild mitochondrial and clinical phenotype in Fanconi anemia
por: Bottega, Roberta, et al.
Publicado: (2018)

Does FANCA Assist CENP-E in Architectural Organization of Chromosomes at Spindle Equator?
por: El-Arabey, Amr Ahmed, et al.
Publicado: (2018)

A germline FANCA alteration that is associated with increased sensitivity to DNA damaging agents
por: Wilkes, David C., et al.
Publicado: (2017)

Structural basis of the fanconi anemia-associated mutations within the FANCA and FANCG complex
por: Jeong, Eunyoung, et al.
Publicado: (2020)

A novel duplication polymorphism in the FANCA promoter and its association with breast and ovarian cancer
por: Thompson, Ella, et al.
Publicado: (2005)

FANCA Gene Mutations with 8 Novel Molecular Changes in Indian Fanconi Anemia Patients
por: Solanki, Avani, et al.
Publicado: (2016)

Esophageal cancer as initial presentation of Fanconi anemia in patients with a hypomorphic FANCA variant
por: Lach, Francis P., et al.
Publicado: (2020)

Determination of the phylogenetic origins of the Árpád Dynasty based on Y chromosome sequencing of Béla the Third
por: Nagy, Péter L., et al.
Publicado: (2020)

Genetic variants in Fanconi Anemia Pathway Genes BRCA2 and FANCA Predict Melanoma Survival
por: Yin, Jieyun, et al.
Publicado: (2014)

A rare FANCA gene variation as a breast cancer susceptibility allele in an Iranian population
por: Abbasi, Sakineh, et al.
Publicado: (2017)

SIK2 kinase synthetic lethality is driven by spindle assembly defects in FANCA‐deficient cells
por: Chan, Ka‐Kui, et al.
Publicado: (2021)

FANCA deficiency promotes leukaemic progression by allowing the emergence of cells carrying oncogenic driver mutations
por: Pawlikowska, Patrycja, et al.
Publicado: (2023)

A Mutation in the MYBL2-1 Gene Is Associated with Purple Pigmentation in Brassica oleracea
por: Khusnutdinov, Emil, et al.
Publicado: (2022)

Delineating the role of FANCA in glucose-stimulated insulin secretion in β cells through its protein interactome
por: Lagundžin, Dragana, et al.
Publicado: (2019)

Novel FANCA mutation in the first fully-diagnosed patient with Fanconi anemia in Polish population – case report
por: Repczynska, Anna, et al.
Publicado: (2020)

A Multiple Primary Malignancy Patient With FANCA Gene Mutation: A Case Report and Literature Review
por: Xia, Qing, et al.
Publicado: (2020)

Aggressive prostate cancer with somatic loss of the homologous recombination repair gene FANCA: a case report
por: Hongo, Hiroshi, et al.
Publicado: (2020)

FANCA基因新复合杂合突变致范可尼贫血一例
Publicado: (2020)

Altered Mitochondrial Dynamic in Lymphoblasts and Fibroblasts Mutated for FANCA-A Gene: The Central Role of DRP1
por: Bertola, Nadia, et al.
Publicado: (2023)

V(D)J recombination process and the Pre-B to immature B-cells transition are altered in Fanca(−/−) mice
por: Nguyen, Thuy Vy, et al.
Publicado: (2016)

Generating New FANCA-Deficient HNSCC Cell Lines by Genomic Editing Recapitulates the Cellular Phenotypes of Fanconi Anemia
por: Errazquin, Ricardo, et al.
Publicado: (2021)

Mutated FANCA Gene Role in the Modulation of Energy Metabolism and Mitochondrial Dynamics in Head and Neck Squamous Cell Carcinoma
por: Bertola, Nadia, et al.
Publicado: (2022)

Next-generation sequencing reveals novel variants and large deletion in FANCA gene in Polish family with Fanconi anemia
por: Repczynska, Anna, et al.
Publicado: (2022)

Fanca deficiency reduces A/T transitions in somatic hypermutation and alters class switch recombination junctions in mouse B cells
por: Nguyen, Thuy Vy, et al.
Publicado: (2014)

High frequency of exon 15 deletion in the FANCA gene in Tunisian patients affected with Fanconi anemia disease: implication for diagnosis
por: Amouri, Ahlem, et al.
Publicado: (2014)

Clinical Benefit With PARP Inhibitor for Pathogenic Germline FANCA-Mutated Relapsed Epithelial Ovarian Cancer: A Case Report
por: Qian, Bing, et al.
Publicado: (2022)

Durable response to olaparib combined low-dose cisplatin in advanced hepatocellular carcinoma with FANCA mutation: A case report
por: Lai, Yi-Hsuan, et al.
Publicado: (2022)

VEGFA/VEGFR2-targeted therapies prevent the VEGFA-induced proliferation of regulatory T cells in cancer
por: Terme, Magali, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_80udj38gkoti1tb5q65kima10k