Craniofacial Development Is Fine-Tuned by Sox2

The precise control of neural crest stem cell delamination, migration and differentiation ensures proper craniofacial and head development. Sox2 shapes the ontogeny of the cranial neural crest to ensure precision of the cell flow in the developing head. Here, we review how Sox2 orchestrates signals...

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Detalles Bibliográficos
Autores principales: Mandalos, Nikolaos Panagiotis, Dimou, Aikaterini, Gavala, Maria Angeliki, Lambraki, Efstathia, Remboutsika, Eumorphia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956624/
https://www.ncbi.nlm.nih.gov/pubmed/36833308
http://dx.doi.org/10.3390/genes14020380
Descripción
Sumario:The precise control of neural crest stem cell delamination, migration and differentiation ensures proper craniofacial and head development. Sox2 shapes the ontogeny of the cranial neural crest to ensure precision of the cell flow in the developing head. Here, we review how Sox2 orchestrates signals that control these complex developmental processes.

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