Craniofacial Development Is Fine-Tuned by Sox2

The precise control of neural crest stem cell delamination, migration and differentiation ensures proper craniofacial and head development. Sox2 shapes the ontogeny of the cranial neural crest to ensure precision of the cell flow in the developing head. Here, we review how Sox2 orchestrates signals...

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Autores principales: Mandalos, Nikolaos Panagiotis, Dimou, Aikaterini, Gavala, Maria Angeliki, Lambraki, Efstathia, Remboutsika, Eumorphia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Opinion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956624/
https://www.ncbi.nlm.nih.gov/pubmed/36833308
http://dx.doi.org/10.3390/genes14020380
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author Mandalos, Nikolaos Panagiotis
Dimou, Aikaterini
Gavala, Maria Angeliki
Lambraki, Efstathia
Remboutsika, Eumorphia
author_facet Mandalos, Nikolaos Panagiotis
Dimou, Aikaterini
Gavala, Maria Angeliki
Lambraki, Efstathia
Remboutsika, Eumorphia
author_sort Mandalos, Nikolaos Panagiotis
collection PubMed
description The precise control of neural crest stem cell delamination, migration and differentiation ensures proper craniofacial and head development. Sox2 shapes the ontogeny of the cranial neural crest to ensure precision of the cell flow in the developing head. Here, we review how Sox2 orchestrates signals that control these complex developmental processes.
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spelling pubmed-99566242023-02-25 Craniofacial Development Is Fine-Tuned by Sox2 Mandalos, Nikolaos Panagiotis Dimou, Aikaterini Gavala, Maria Angeliki Lambraki, Efstathia Remboutsika, Eumorphia Genes (Basel) Opinion The precise control of neural crest stem cell delamination, migration and differentiation ensures proper craniofacial and head development. Sox2 shapes the ontogeny of the cranial neural crest to ensure precision of the cell flow in the developing head. Here, we review how Sox2 orchestrates signals that control these complex developmental processes. MDPI 2023-01-31 /pmc/articles/PMC9956624/ /pubmed/36833308 http://dx.doi.org/10.3390/genes14020380 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Opinion
Mandalos, Nikolaos Panagiotis
Dimou, Aikaterini
Gavala, Maria Angeliki
Lambraki, Efstathia
Remboutsika, Eumorphia
Craniofacial Development Is Fine-Tuned by Sox2
title Craniofacial Development Is Fine-Tuned by Sox2
title_full Craniofacial Development Is Fine-Tuned by Sox2
title_fullStr Craniofacial Development Is Fine-Tuned by Sox2
title_full_unstemmed Craniofacial Development Is Fine-Tuned by Sox2
title_short Craniofacial Development Is Fine-Tuned by Sox2
title_sort craniofacial development is fine-tuned by sox2
topic Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956624/
https://www.ncbi.nlm.nih.gov/pubmed/36833308
http://dx.doi.org/10.3390/genes14020380
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AT gavalamariaangeliki craniofacialdevelopmentisfinetunedbysox2
AT lambrakiefstathia craniofacialdevelopmentisfinetunedbysox2
AT remboutsikaeumorphia craniofacialdevelopmentisfinetunedbysox2

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