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Severe Periodontitis Increases the Risk of Oral Frailty: A Six-Year Follow-Up Study from Kashiwa Cohort Study

Oral frailty, overlapping a decline in multi-faceted oral functions and often seen in older adults, increases risks of adverse health outcomes, thereby necessitating earlier measures. Tooth loss, a major element of oral frailty, is mainly caused by periodontal disease and is an irreversible event. T...

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Autores principales: Nishimoto, Misa, Tanaka, Tomoki, Hirano, Hirohiko, Watanabe, Yutaka, Ohara, Yuki, Shirobe, Maki, Iijima, Katsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956982/
https://www.ncbi.nlm.nih.gov/pubmed/36826367
http://dx.doi.org/10.3390/geriatrics8010025
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author Nishimoto, Misa
Tanaka, Tomoki
Hirano, Hirohiko
Watanabe, Yutaka
Ohara, Yuki
Shirobe, Maki
Iijima, Katsuya
author_facet Nishimoto, Misa
Tanaka, Tomoki
Hirano, Hirohiko
Watanabe, Yutaka
Ohara, Yuki
Shirobe, Maki
Iijima, Katsuya
author_sort Nishimoto, Misa
collection PubMed
description Oral frailty, overlapping a decline in multi-faceted oral functions and often seen in older adults, increases risks of adverse health outcomes, thereby necessitating earlier measures. Tooth loss, a major element of oral frailty, is mainly caused by periodontal disease and is an irreversible event. Therefore, this study aimed to clarify whether advanced periodontal disease increases the risks of “new-onset” oral frailty through a longitudinal analysis based on the 2012 baseline survey of the Kashiwa cohort and the follow-up assessments conducted in 2013, 2014, 2016, and 2018. The participants were disability-free, non-orally frail older adults living in Kashiwa City. Of the 1234 participants (72.2 ± 5.1 years old; 50.8% men) analyzed in this study, oral frailty occurred in 23.1% within the six-year period. The group with Community Periodontal Index (CPI) ≥ 3 at baseline had no significant difference in the risk of oral frailty compared with CPI ≤ 2; however, CPI4 at baseline was related to the increased risk of oral frailty compared with CPI ≤ 3 (an adjusted hazard ratio (95% confidence interval): 1.42 (1.12–1.81). Conclusively, severe periodontitis (CPI4) might be associated with new-onset oral frailty, suggesting that prevention of periodontal disease could contribute to oral frailty prevention.
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spelling pubmed-99569822023-02-25 Severe Periodontitis Increases the Risk of Oral Frailty: A Six-Year Follow-Up Study from Kashiwa Cohort Study Nishimoto, Misa Tanaka, Tomoki Hirano, Hirohiko Watanabe, Yutaka Ohara, Yuki Shirobe, Maki Iijima, Katsuya Geriatrics (Basel) Article Oral frailty, overlapping a decline in multi-faceted oral functions and often seen in older adults, increases risks of adverse health outcomes, thereby necessitating earlier measures. Tooth loss, a major element of oral frailty, is mainly caused by periodontal disease and is an irreversible event. Therefore, this study aimed to clarify whether advanced periodontal disease increases the risks of “new-onset” oral frailty through a longitudinal analysis based on the 2012 baseline survey of the Kashiwa cohort and the follow-up assessments conducted in 2013, 2014, 2016, and 2018. The participants were disability-free, non-orally frail older adults living in Kashiwa City. Of the 1234 participants (72.2 ± 5.1 years old; 50.8% men) analyzed in this study, oral frailty occurred in 23.1% within the six-year period. The group with Community Periodontal Index (CPI) ≥ 3 at baseline had no significant difference in the risk of oral frailty compared with CPI ≤ 2; however, CPI4 at baseline was related to the increased risk of oral frailty compared with CPI ≤ 3 (an adjusted hazard ratio (95% confidence interval): 1.42 (1.12–1.81). Conclusively, severe periodontitis (CPI4) might be associated with new-onset oral frailty, suggesting that prevention of periodontal disease could contribute to oral frailty prevention. MDPI 2023-02-13 /pmc/articles/PMC9956982/ /pubmed/36826367 http://dx.doi.org/10.3390/geriatrics8010025 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Nishimoto, Misa
Tanaka, Tomoki
Hirano, Hirohiko
Watanabe, Yutaka
Ohara, Yuki
Shirobe, Maki
Iijima, Katsuya
Severe Periodontitis Increases the Risk of Oral Frailty: A Six-Year Follow-Up Study from Kashiwa Cohort Study
title Severe Periodontitis Increases the Risk of Oral Frailty: A Six-Year Follow-Up Study from Kashiwa Cohort Study
title_full Severe Periodontitis Increases the Risk of Oral Frailty: A Six-Year Follow-Up Study from Kashiwa Cohort Study
title_fullStr Severe Periodontitis Increases the Risk of Oral Frailty: A Six-Year Follow-Up Study from Kashiwa Cohort Study
title_full_unstemmed Severe Periodontitis Increases the Risk of Oral Frailty: A Six-Year Follow-Up Study from Kashiwa Cohort Study
title_short Severe Periodontitis Increases the Risk of Oral Frailty: A Six-Year Follow-Up Study from Kashiwa Cohort Study
title_sort severe periodontitis increases the risk of oral frailty: a six-year follow-up study from kashiwa cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9956982/
https://www.ncbi.nlm.nih.gov/pubmed/36826367
http://dx.doi.org/10.3390/geriatrics8010025
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