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Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction

Stinging nettle (Urtica dioica L.) is one fantastic plant widely used in folk medicine, pharmacy, cosmetics, and food. This plant’s popularity may be explained by its chemical composition, containing a wide range of compounds significant for human health and diet. This study aimed to investigate ext...

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Autores principales: Đurović, Saša, Pezo, Lato, Gašić, Uroš, Gorjanović, Stanislava, Pastor, Ferenc, Bazarnova, Julia G., Smyatskaya, Yulia A., Zeković, Zoran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957156/
https://www.ncbi.nlm.nih.gov/pubmed/36832884
http://dx.doi.org/10.3390/foods12040809
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author Đurović, Saša
Pezo, Lato
Gašić, Uroš
Gorjanović, Stanislava
Pastor, Ferenc
Bazarnova, Julia G.
Smyatskaya, Yulia A.
Zeković, Zoran
author_facet Đurović, Saša
Pezo, Lato
Gašić, Uroš
Gorjanović, Stanislava
Pastor, Ferenc
Bazarnova, Julia G.
Smyatskaya, Yulia A.
Zeković, Zoran
author_sort Đurović, Saša
collection PubMed
description Stinging nettle (Urtica dioica L.) is one fantastic plant widely used in folk medicine, pharmacy, cosmetics, and food. This plant’s popularity may be explained by its chemical composition, containing a wide range of compounds significant for human health and diet. This study aimed to investigate extracts of exhausted stinging nettle leaves after supercritical fluid extraction obtained using ultrasound and microwave techniques. Extracts were analyzed to obtain insight into the chemical composition and biological activity. These extracts were shown to be more potent than those of previously untreated leaves. The principal component analysis was applied as a pattern recognition tool to visualize the antioxidant capacity and cytotoxic activity of extract obtained from exhausted stinging nettle leaves. An artificial neural network model is presented for the prediction of the antioxidant activity of samples according to polyphenolic profile data, showing a suitable anticipation property (the r(2) value during the training cycle for output variables was 0.999).
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spelling pubmed-99571562023-02-25 Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction Đurović, Saša Pezo, Lato Gašić, Uroš Gorjanović, Stanislava Pastor, Ferenc Bazarnova, Julia G. Smyatskaya, Yulia A. Zeković, Zoran Foods Article Stinging nettle (Urtica dioica L.) is one fantastic plant widely used in folk medicine, pharmacy, cosmetics, and food. This plant’s popularity may be explained by its chemical composition, containing a wide range of compounds significant for human health and diet. This study aimed to investigate extracts of exhausted stinging nettle leaves after supercritical fluid extraction obtained using ultrasound and microwave techniques. Extracts were analyzed to obtain insight into the chemical composition and biological activity. These extracts were shown to be more potent than those of previously untreated leaves. The principal component analysis was applied as a pattern recognition tool to visualize the antioxidant capacity and cytotoxic activity of extract obtained from exhausted stinging nettle leaves. An artificial neural network model is presented for the prediction of the antioxidant activity of samples according to polyphenolic profile data, showing a suitable anticipation property (the r(2) value during the training cycle for output variables was 0.999). MDPI 2023-02-14 /pmc/articles/PMC9957156/ /pubmed/36832884 http://dx.doi.org/10.3390/foods12040809 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Đurović, Saša
Pezo, Lato
Gašić, Uroš
Gorjanović, Stanislava
Pastor, Ferenc
Bazarnova, Julia G.
Smyatskaya, Yulia A.
Zeković, Zoran
Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction
title Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction
title_full Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction
title_fullStr Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction
title_full_unstemmed Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction
title_short Recovery of Biologically Active Compounds from Stinging Nettle Leaves Part II: Processing of Exhausted Plant Material after Supercritical Fluid Extraction
title_sort recovery of biologically active compounds from stinging nettle leaves part ii: processing of exhausted plant material after supercritical fluid extraction
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957156/
https://www.ncbi.nlm.nih.gov/pubmed/36832884
http://dx.doi.org/10.3390/foods12040809
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