Cargando…

Identification of TRPC6 as a Novel Diagnostic Biomarker of PM-Induced Chronic Obstructive Pulmonary Disease Using Machine Learning Models

Chronic obstructive pulmonary disease (COPD) was the third most prevalent cause of mortality worldwide in 2010; it results from a progressive and fatal deterioration of lung function because of cigarette smoking and particulate matter (PM). Therefore, it is important to identify molecular biomarkers...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dhong, Kyu-Ree, Lee, Jae-Hyeong, Yoon, You-Rim, Park, Hye-Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957274/ https://www.ncbi.nlm.nih.gov/pubmed/36833211 http://dx.doi.org/10.3390/genes14020284

Ejemplares similares

Pediococcus Pentosaceus from the Sweet Potato Fermented Ger-Minated Brown Rice Can Inhibit Type I Hypersensitivity in RBL-2H3 Cell and BALB/c Mice Models
por: Dhong, Kyu-Ree, et al.
Publicado: (2021)

The contribution of TRPC1, TRPC3, TRPC5 and TRPC6 to touch and hearing
por: Sexton, Jane E., et al.
Publicado: (2016)

Effects of TRPC1 on epithelial mesenchymal transition in human airway in chronic obstructive pulmonary disease
por: Xu, Feng, et al.
Publicado: (2017)

Lactic Acid Bacteria Fermented Cordyceps militaris (GRC-SC11) Suppresses IgE Mediated Mast Cell Activation and Type I Hypersensitive Allergic Murine Model
por: Phull, Abdul-Rehman, et al.
Publicado: (2021)

Immunostimulatory Activity of Cordyceps militaris Fermented with Pediococcus pentosaceus SC11 Isolated from a Salted Small Octopus in Cyclophosphamide-Induced Immunocompromised Mice and Its Inhibitory Activity against SARS-CoV 3CL Protease
por: Dhong, Kyu-Ree, et al.
Publicado: (2022)

Identification of diagnostic biomarkers for idiopathic pulmonary hypertension with metabolic syndrome by bioinformatics and machine learning
por: Lu, Wenzhang, et al.
Publicado: (2023)

TRPC3 channel gating by lipids requires localization at the ER/PM junctions defined by STIM1
por: Liu, Haiping, et al.
Publicado: (2022)

The roles of G proteins in the activation of TRPC4 and TRPC5 transient receptor potential channels
por: Kim, Hana, et al.
Publicado: (2012)

Corticolimbic Expression of TRPC4 and TRPC5 Channels in the Rodent Brain
por: Fowler, Melissa A., et al.
Publicado: (2007)

Structural identification of riluzole-binding site on human TRPC5
por: Yang, Yaxiong, et al.
Publicado: (2022)

Combination of Systemic Inflammatory Biomarkers in Assessment of Chronic Obstructive Pulmonary Disease: Diagnostic Performance and Identification of Networks and Clusters
por: Hlapčić, Iva, et al.
Publicado: (2020)

Machine-Learning Algorithm-Based Prediction of Diagnostic Gene Biomarkers Related to Immune Infiltration in Patients With Chronic Obstructive Pulmonary Disease
por: Zhang, Yuepeng, et al.
Publicado: (2022)

Novel Targets for Stroke Therapy: Special Focus on TRPC Channels and TRPC6
por: Liu, Lu, et al.
Publicado: (2020)

Diacylglycerol regulates acute hypoxic pulmonary vasoconstriction via TRPC6
por: Fuchs, Beate, et al.
Publicado: (2011)

Identification and validation of diagnostic signature genes in non-obstructive azoospermia by machine learning
por: Ran, Lingxiang, et al.
Publicado: (2023)

Identification of biomarkers associated with clinical severity of chronic obstructive pulmonary disease
por: Zhang, Jie, et al.
Publicado: (2020)

Contribution of Zinc-Dependent Delayed Calcium Influx via TRPC5 in Oxidative Neuronal Death and its Prevention by Novel TRPC Antagonist
por: Park, Sang Eun, et al.
Publicado: (2018)

Herbal Formula, PM014, Attenuates Lung Inflammation in a Murine Model of Chronic Obstructive Pulmonary Disease
por: Lee, Hyojung, et al.
Publicado: (2012)

TRPC3 and NALCN channels drive pacemaking in substantia nigra dopaminergic neurons
por: Um, Ki Bum, et al.
Publicado: (2021)

Altered expression of PPAR-γ and TRPC in neonatal rats with persistent pulmonary hypertension
por: Du, Yanna, et al.
Publicado: (2017)

TRPC Channels in Cardiac Plasticity
por: Numaga-Tomita, Takuro, et al.
Publicado: (2020)

TRPC Channels in the SOCE Scenario
por: Lopez, Jose J., et al.
Publicado: (2020)

Increasing the expression of calcium-permeable TRPC3 and TRPC7 channels enhances constitutive secretion
por: Lavender, Verna, et al.
Publicado: (2008)

Crucial Role of TRPC1 and TRPC4 in Cystitis-Induced Neuronal Sprouting and Bladder Overactivity
por: Boudes, Mathieu, et al.
Publicado: (2013)

TRPC3, but not TRPC1, as a good therapeutic target for standalone or complementary treatment of DMD
por: Creisméas, Anna, et al.
Publicado: (2021)

Effect of a Dose-Escalation Regimen for Improving Adherence to Roflumilast in Patients with Chronic Obstructive Pulmonary Disease
por: Hwang, Hyunjung, et al.
Publicado: (2015)

The Effects and Pathogenesis of PM2.5 and Its Components on Chronic Obstructive Pulmonary Disease
por: Wang, Qi, et al.
Publicado: (2023)

Chronic obstructive pulmonary disease: MicroRNAs and exosomes as new diagnostic and therapeutic biomarkers
por: Salimian, Jafar, et al.
Publicado: (2018)

Acute exacerbations of chronic obstructive pulmonary disease: in search of diagnostic biomarkers and treatable traits
por: Mathioudakis, Alexander G, et al.
Publicado: (2020)

Identification of lipid biomarker from serum in patients with chronic obstructive pulmonary disease
por: Liu, Ding, et al.
Publicado: (2020)

TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells
por: Quick, Kathryn, et al.
Publicado: (2012)

Specific Upregulation of TRPC1 and TRPC5 Channels by Mineralocorticoid Pathway in Adult Rat Ventricular Cardiomyocytes
por: Bartoli, Fiona, et al.
Publicado: (2019)

Analysis of the Effect of the TRPC4/TRPC5 Blocker, ML204, in Sucrose-Induced Metabolic Imbalance
por: Araújo, Mizael C., et al.
Publicado: (2023)

Stim-activated TRPC-ORAI channels in pulmonary hypertension induced by chronic intermittent hypoxia
por: Castillo-Galán, Sebastian, et al.
Publicado: (2020)

TRPC1: Getting physical in space
por: Ambudkar, Indu S
Publicado: (2013)

TRPC channels in exercise-mimetic therapy
por: Numaga-Tomita, Takuro, et al.
Publicado: (2018)

TRPC expression in mesenchymal stem cells
por: Torossian, Frederic, et al.
Publicado: (2010)

TRPC3 Channels in Cardiac Fibrosis
por: Numaga-Tomita, Takuro, et al.
Publicado: (2017)

TRPC Channels in Proteinuric Kidney Diseases
por: Hall, Gentzon, et al.
Publicado: (2019)

Machine learning in chronic obstructive pulmonary disease
por: Zhang, Bochao, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_3mf08kgl9f8i6ts2eslju12bq7