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Low-Cost Pseudo-Anthropomorphic PVA-C and Cellulose Lung Phantom for Ultrasound-Guided Interventions

A low-cost custom-made pseudo-anthropomorphic lung phantom, offering a model for ultrasound-guided interventions, is presented. The phantom is a rectangular solidstructure fabricated with polyvinyl alcohol cryogel (PVA-C) and cellulose to mimic the healthy parenchyma. The pathologies of interest wer...

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Autores principales: Arteaga-Marrero, Natalia, Villa, Enrique, Llanos González, Ana Belén, Gómez Gil, Marta Elena, Fernández, Orlando Acosta, Ruiz-Alzola, Juan, González-Fernández, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957311/
https://www.ncbi.nlm.nih.gov/pubmed/36826245
http://dx.doi.org/10.3390/gels9020074
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author Arteaga-Marrero, Natalia
Villa, Enrique
Llanos González, Ana Belén
Gómez Gil, Marta Elena
Fernández, Orlando Acosta
Ruiz-Alzola, Juan
González-Fernández, Javier
author_facet Arteaga-Marrero, Natalia
Villa, Enrique
Llanos González, Ana Belén
Gómez Gil, Marta Elena
Fernández, Orlando Acosta
Ruiz-Alzola, Juan
González-Fernández, Javier
author_sort Arteaga-Marrero, Natalia
collection PubMed
description A low-cost custom-made pseudo-anthropomorphic lung phantom, offering a model for ultrasound-guided interventions, is presented. The phantom is a rectangular solidstructure fabricated with polyvinyl alcohol cryogel (PVA-C) and cellulose to mimic the healthy parenchyma. The pathologies of interest were embedded as inclusions containing gaseous, liquid, or solid materials. The ribs were 3D-printed using polyethylene terephthalate, and the pleura was made of a bidimensional reticle based on PVA-C. The healthy and pathological tissues were mimicked to display acoustic and echoic properties similar to that of soft tissues. Theflexible fabrication process facilitated the modification of the physical and acoustic properties of the phantom. The phantom’s manufacture offers flexibility regarding the number, shape, location, and composition of the inclusions and the insertion of ribs and pleura. In-plane and out-of-plane needle insertions, fine needle aspiration, and core needle biopsy were performed under ultrasound image guidance. The mimicked tissues displayed a resistance and recoil effect typically encountered in a real scenario for a pneumothorax, abscesses, and neoplasms. The presented phantom accurately replicated thoracic tissues (lung, ribs, and pleura) and associated pathologies providing a useful tool for training ultrasound-guided procedures.
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spelling pubmed-99573112023-02-25 Low-Cost Pseudo-Anthropomorphic PVA-C and Cellulose Lung Phantom for Ultrasound-Guided Interventions Arteaga-Marrero, Natalia Villa, Enrique Llanos González, Ana Belén Gómez Gil, Marta Elena Fernández, Orlando Acosta Ruiz-Alzola, Juan González-Fernández, Javier Gels Article A low-cost custom-made pseudo-anthropomorphic lung phantom, offering a model for ultrasound-guided interventions, is presented. The phantom is a rectangular solidstructure fabricated with polyvinyl alcohol cryogel (PVA-C) and cellulose to mimic the healthy parenchyma. The pathologies of interest were embedded as inclusions containing gaseous, liquid, or solid materials. The ribs were 3D-printed using polyethylene terephthalate, and the pleura was made of a bidimensional reticle based on PVA-C. The healthy and pathological tissues were mimicked to display acoustic and echoic properties similar to that of soft tissues. Theflexible fabrication process facilitated the modification of the physical and acoustic properties of the phantom. The phantom’s manufacture offers flexibility regarding the number, shape, location, and composition of the inclusions and the insertion of ribs and pleura. In-plane and out-of-plane needle insertions, fine needle aspiration, and core needle biopsy were performed under ultrasound image guidance. The mimicked tissues displayed a resistance and recoil effect typically encountered in a real scenario for a pneumothorax, abscesses, and neoplasms. The presented phantom accurately replicated thoracic tissues (lung, ribs, and pleura) and associated pathologies providing a useful tool for training ultrasound-guided procedures. MDPI 2023-01-17 /pmc/articles/PMC9957311/ /pubmed/36826245 http://dx.doi.org/10.3390/gels9020074 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Arteaga-Marrero, Natalia
Villa, Enrique
Llanos González, Ana Belén
Gómez Gil, Marta Elena
Fernández, Orlando Acosta
Ruiz-Alzola, Juan
González-Fernández, Javier
Low-Cost Pseudo-Anthropomorphic PVA-C and Cellulose Lung Phantom for Ultrasound-Guided Interventions
title Low-Cost Pseudo-Anthropomorphic PVA-C and Cellulose Lung Phantom for Ultrasound-Guided Interventions
title_full Low-Cost Pseudo-Anthropomorphic PVA-C and Cellulose Lung Phantom for Ultrasound-Guided Interventions
title_fullStr Low-Cost Pseudo-Anthropomorphic PVA-C and Cellulose Lung Phantom for Ultrasound-Guided Interventions
title_full_unstemmed Low-Cost Pseudo-Anthropomorphic PVA-C and Cellulose Lung Phantom for Ultrasound-Guided Interventions
title_short Low-Cost Pseudo-Anthropomorphic PVA-C and Cellulose Lung Phantom for Ultrasound-Guided Interventions
title_sort low-cost pseudo-anthropomorphic pva-c and cellulose lung phantom for ultrasound-guided interventions
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957311/
https://www.ncbi.nlm.nih.gov/pubmed/36826245
http://dx.doi.org/10.3390/gels9020074
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