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A Rare Case of Primary Peritoneal Carcinoma With Large Bowel Metastasis
Primary serous peritoneal carcinoma (PPC) is a rare malignancy often presenting with a significant disease burden and a poor prognosis. A 65-year-old female was seen in the surgical outpatient clinic with a two-month history of weight loss, altered bowel habits and a CT scan characterizing a heterog...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957569/ https://www.ncbi.nlm.nih.gov/pubmed/36843709 http://dx.doi.org/10.7759/cureus.34167 |
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author | Jangam, Aishwarya Math, Vanitha |
author_facet | Jangam, Aishwarya Math, Vanitha |
author_sort | Jangam, Aishwarya |
collection | PubMed |
description | Primary serous peritoneal carcinoma (PPC) is a rare malignancy often presenting with a significant disease burden and a poor prognosis. A 65-year-old female was seen in the surgical outpatient clinic with a two-month history of weight loss, altered bowel habits and a CT scan characterizing a heterogenous right paracolic gutter mass and suspicious liver lesions. At colonoscopy, a prominent appendiceal orifice was biopsied to be poorly differentiated carcinoma favouring gynaecological tract origin. The patient was admitted with an acute small bowel obstruction secondary to progression of metastases and underwent neoadjuvant chemotherapy with a near complete response on repeat staging. A debulking hysterectomy, bilateral salpingo-oophorectomy, pelvic peritonectomy and small bowel nodule excision were performed. The diagnosis of PPC was confirmed when no malignancy was found in the pelvic organs. The presence of intraluminal colonic metastasis with PPC is exceedingly rare with this being only the third such case in the literature. |
format | Online Article Text |
id | pubmed-9957569 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-99575692023-02-25 A Rare Case of Primary Peritoneal Carcinoma With Large Bowel Metastasis Jangam, Aishwarya Math, Vanitha Cureus Obstetrics/Gynecology Primary serous peritoneal carcinoma (PPC) is a rare malignancy often presenting with a significant disease burden and a poor prognosis. A 65-year-old female was seen in the surgical outpatient clinic with a two-month history of weight loss, altered bowel habits and a CT scan characterizing a heterogenous right paracolic gutter mass and suspicious liver lesions. At colonoscopy, a prominent appendiceal orifice was biopsied to be poorly differentiated carcinoma favouring gynaecological tract origin. The patient was admitted with an acute small bowel obstruction secondary to progression of metastases and underwent neoadjuvant chemotherapy with a near complete response on repeat staging. A debulking hysterectomy, bilateral salpingo-oophorectomy, pelvic peritonectomy and small bowel nodule excision were performed. The diagnosis of PPC was confirmed when no malignancy was found in the pelvic organs. The presence of intraluminal colonic metastasis with PPC is exceedingly rare with this being only the third such case in the literature. Cureus 2023-01-24 /pmc/articles/PMC9957569/ /pubmed/36843709 http://dx.doi.org/10.7759/cureus.34167 Text en Copyright © 2023, Jangam et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Obstetrics/Gynecology Jangam, Aishwarya Math, Vanitha A Rare Case of Primary Peritoneal Carcinoma With Large Bowel Metastasis |
title | A Rare Case of Primary Peritoneal Carcinoma With Large Bowel Metastasis |
title_full | A Rare Case of Primary Peritoneal Carcinoma With Large Bowel Metastasis |
title_fullStr | A Rare Case of Primary Peritoneal Carcinoma With Large Bowel Metastasis |
title_full_unstemmed | A Rare Case of Primary Peritoneal Carcinoma With Large Bowel Metastasis |
title_short | A Rare Case of Primary Peritoneal Carcinoma With Large Bowel Metastasis |
title_sort | rare case of primary peritoneal carcinoma with large bowel metastasis |
topic | Obstetrics/Gynecology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957569/ https://www.ncbi.nlm.nih.gov/pubmed/36843709 http://dx.doi.org/10.7759/cureus.34167 |
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