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Probing the Role of CYP2 Enzymes in the Atropselective Metabolism of Polychlorinated Biphenyls Using Liver Microsomes from Transgenic Mouse Models

[Image: see text] Chiral polychlorinated biphenyls (PCB) are environmentally relevant developmental neurotoxicants. Because their hydroxylated metabolites (OH-PCBs) are also neurotoxic, it is necessary to determine how PCB metabolism affects the developing brain, for example, in mouse models. Becaus...

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Detalles Bibliográficos
Autores principales:	Lehmler, Hans-Joachim, Uwimana, Eric, Dean, Laura E., Kovalchuk, Nataliia, Zhang, Qing-Yu, Ding, Xinxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957597/ https://www.ncbi.nlm.nih.gov/pubmed/36473170 http://dx.doi.org/10.1021/acs.chemrestox.2c00276

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