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Nanosized drug delivery strategies in osteosarcoma chemotherapy
Despite recent developments worldwide in the therapeutic care of osteosarcoma (OS), the ongoing challenges in overcoming limitations and side effects of chemotherapy drugs warrant new strategies to improve overall patient survival. Spurred by rapid progress in biomedicine, nanobiotechnology, and mat...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AIP Publishing LLC
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957606/ https://www.ncbi.nlm.nih.gov/pubmed/36845905 http://dx.doi.org/10.1063/5.0137026 |
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author | Chen, Chenglong Wang, Shidong Wang, Juan Yao, Fangzhou Tang, Xiaodong Guo, Wei |
author_facet | Chen, Chenglong Wang, Shidong Wang, Juan Yao, Fangzhou Tang, Xiaodong Guo, Wei |
author_sort | Chen, Chenglong |
collection | PubMed |
description | Despite recent developments worldwide in the therapeutic care of osteosarcoma (OS), the ongoing challenges in overcoming limitations and side effects of chemotherapy drugs warrant new strategies to improve overall patient survival. Spurred by rapid progress in biomedicine, nanobiotechnology, and materials chemistry, chemotherapeutic drug delivery in treatment of OS has become possible in recent years. Here, we review recent advances in the design of drug delivery system, especially for chemotherapeutic drugs in OS, and discuss the relative merits in trials along with future therapeutic options. These advances may pave the way for novel therapies requisite for patients with OS. |
format | Online Article Text |
id | pubmed-9957606 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | AIP Publishing LLC |
record_format | MEDLINE/PubMed |
spelling | pubmed-99576062023-02-25 Nanosized drug delivery strategies in osteosarcoma chemotherapy Chen, Chenglong Wang, Shidong Wang, Juan Yao, Fangzhou Tang, Xiaodong Guo, Wei APL Bioeng Reviews Despite recent developments worldwide in the therapeutic care of osteosarcoma (OS), the ongoing challenges in overcoming limitations and side effects of chemotherapy drugs warrant new strategies to improve overall patient survival. Spurred by rapid progress in biomedicine, nanobiotechnology, and materials chemistry, chemotherapeutic drug delivery in treatment of OS has become possible in recent years. Here, we review recent advances in the design of drug delivery system, especially for chemotherapeutic drugs in OS, and discuss the relative merits in trials along with future therapeutic options. These advances may pave the way for novel therapies requisite for patients with OS. AIP Publishing LLC 2023-02-23 /pmc/articles/PMC9957606/ /pubmed/36845905 http://dx.doi.org/10.1063/5.0137026 Text en © 2023 Author(s). https://creativecommons.org/licenses/by/4.0/All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ). |
spellingShingle | Reviews Chen, Chenglong Wang, Shidong Wang, Juan Yao, Fangzhou Tang, Xiaodong Guo, Wei Nanosized drug delivery strategies in osteosarcoma chemotherapy |
title | Nanosized drug delivery strategies in osteosarcoma chemotherapy |
title_full | Nanosized drug delivery strategies in osteosarcoma chemotherapy |
title_fullStr | Nanosized drug delivery strategies in osteosarcoma chemotherapy |
title_full_unstemmed | Nanosized drug delivery strategies in osteosarcoma chemotherapy |
title_short | Nanosized drug delivery strategies in osteosarcoma chemotherapy |
title_sort | nanosized drug delivery strategies in osteosarcoma chemotherapy |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957606/ https://www.ncbi.nlm.nih.gov/pubmed/36845905 http://dx.doi.org/10.1063/5.0137026 |
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