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Nanosized drug delivery strategies in osteosarcoma chemotherapy

Despite recent developments worldwide in the therapeutic care of osteosarcoma (OS), the ongoing challenges in overcoming limitations and side effects of chemotherapy drugs warrant new strategies to improve overall patient survival. Spurred by rapid progress in biomedicine, nanobiotechnology, and mat...

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Autores principales: Chen, Chenglong, Wang, Shidong, Wang, Juan, Yao, Fangzhou, Tang, Xiaodong, Guo, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957606/
https://www.ncbi.nlm.nih.gov/pubmed/36845905
http://dx.doi.org/10.1063/5.0137026
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author Chen, Chenglong
Wang, Shidong
Wang, Juan
Yao, Fangzhou
Tang, Xiaodong
Guo, Wei
author_facet Chen, Chenglong
Wang, Shidong
Wang, Juan
Yao, Fangzhou
Tang, Xiaodong
Guo, Wei
author_sort Chen, Chenglong
collection PubMed
description Despite recent developments worldwide in the therapeutic care of osteosarcoma (OS), the ongoing challenges in overcoming limitations and side effects of chemotherapy drugs warrant new strategies to improve overall patient survival. Spurred by rapid progress in biomedicine, nanobiotechnology, and materials chemistry, chemotherapeutic drug delivery in treatment of OS has become possible in recent years. Here, we review recent advances in the design of drug delivery system, especially for chemotherapeutic drugs in OS, and discuss the relative merits in trials along with future therapeutic options. These advances may pave the way for novel therapies requisite for patients with OS.
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spelling pubmed-99576062023-02-25 Nanosized drug delivery strategies in osteosarcoma chemotherapy Chen, Chenglong Wang, Shidong Wang, Juan Yao, Fangzhou Tang, Xiaodong Guo, Wei APL Bioeng Reviews Despite recent developments worldwide in the therapeutic care of osteosarcoma (OS), the ongoing challenges in overcoming limitations and side effects of chemotherapy drugs warrant new strategies to improve overall patient survival. Spurred by rapid progress in biomedicine, nanobiotechnology, and materials chemistry, chemotherapeutic drug delivery in treatment of OS has become possible in recent years. Here, we review recent advances in the design of drug delivery system, especially for chemotherapeutic drugs in OS, and discuss the relative merits in trials along with future therapeutic options. These advances may pave the way for novel therapies requisite for patients with OS. AIP Publishing LLC 2023-02-23 /pmc/articles/PMC9957606/ /pubmed/36845905 http://dx.doi.org/10.1063/5.0137026 Text en © 2023 Author(s). https://creativecommons.org/licenses/by/4.0/All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ).
spellingShingle Reviews
Chen, Chenglong
Wang, Shidong
Wang, Juan
Yao, Fangzhou
Tang, Xiaodong
Guo, Wei
Nanosized drug delivery strategies in osteosarcoma chemotherapy
title Nanosized drug delivery strategies in osteosarcoma chemotherapy
title_full Nanosized drug delivery strategies in osteosarcoma chemotherapy
title_fullStr Nanosized drug delivery strategies in osteosarcoma chemotherapy
title_full_unstemmed Nanosized drug delivery strategies in osteosarcoma chemotherapy
title_short Nanosized drug delivery strategies in osteosarcoma chemotherapy
title_sort nanosized drug delivery strategies in osteosarcoma chemotherapy
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957606/
https://www.ncbi.nlm.nih.gov/pubmed/36845905
http://dx.doi.org/10.1063/5.0137026
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