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Tumor antigen-loaded AAV vaccine drives protective immunity in a melanoma animal model

We previously described therapeutic opportunities provided by capsid- and expression cassette-optimized adeno-associated virus serotype 6 (AAV6) vectors to suppress tumor growth in both solid and metastatic mouse models by using artificial ovalbumin (OVA) immunogen. In the current study, we further...

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Detalles Bibliográficos
Autores principales: Krotova, Karina, Kuoch (Yoshitomi), Hisae, Caine, Colin, Aslanidi, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957711/
https://www.ncbi.nlm.nih.gov/pubmed/36851984
http://dx.doi.org/10.1016/j.omtm.2023.01.006