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Monitoring the 5′UTR landscape reveals isoform switches to drive translational efficiencies in cancer

Transcriptional and translational control are key determinants of gene expression, however, to what extent these two processes can be collectively coordinated is still poorly understood. Here, we use Nanopore long-read sequencing and cap analysis of gene expression (CAGE-seq) to document the landsca...

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Detalles Bibliográficos
Autores principales:	Weber, Ramona, Ghoshdastider, Umesh, Spies, Daniel, Duré, Clara, Valdivia-Francia, Fabiola, Forny, Merima, Ormiston, Mark, Renz, Peter F., Taborsky, David, Yigit, Merve, Bernasconi, Martino, Yamahachi, Homare, Sendoel, Ataman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957725/ https://www.ncbi.nlm.nih.gov/pubmed/36550360 http://dx.doi.org/10.1038/s41388-022-02578-2

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