RAC1B function is essential for breast cancer stem cell maintenance and chemoresistance of breast tumor cells

Breast cancer stem cells (BCSC) are presumed to be responsible for treatment resistance, tumor recurrence and metastasis of breast tumors. However, development of BCSC-targeting therapies has been held back by their heterogeneity and the lack of BCSC-selective molecular targets. Here, we demonstrate...

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Detalles Bibliográficos
Autores principales: Chen, Fuhui, Gurler, Sevim B., Novo, David, Selli, Cigdem, Alferez, Denis G., Eroglu, Secil, Pavlou, Kyriaki, Zhang, Jingwei, Sims, Andrew H., Humphreys, Neil E., Adamson, Antony, Campbell, Andrew, Sansom, Owen J., Tournier, Cathy, Clarke, Robert B., Brennan, Keith, Streuli, Charles H., Ucar, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957727/
https://www.ncbi.nlm.nih.gov/pubmed/36599922
http://dx.doi.org/10.1038/s41388-022-02574-6

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