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Impaired oxygen extraction and adaptation of intracellular energy metabolism in cerebral small vessel disease
BACKGROUND: We aimed to investigate whether combined phosphorous ((31)P) magnetic resonance spectroscopic imaging (MRSI) and quantitative [Formula: see text] mapping are able to detect alterations of the cerebral oxygen extraction fraction (OEF) and intracellular pH (pH(i)) as markers the of cellula...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957754/ https://www.ncbi.nlm.nih.gov/pubmed/36851996 http://dx.doi.org/10.1016/j.cccb.2023.100162 |