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Impaired oxygen extraction and adaptation of intracellular energy metabolism in cerebral small vessel disease

BACKGROUND: We aimed to investigate whether combined phosphorous ((31)P) magnetic resonance spectroscopic imaging (MRSI) and quantitative [Formula: see text] mapping are able to detect alterations of the cerebral oxygen extraction fraction (OEF) and intracellular pH (pH(i)) as markers the of cellula...

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Detalles Bibliográficos
Autores principales:	Reiländer, Annemarie, Pilatus, Ulrich, Schüre, Jan-Rüdiger, Shrestha, Manoj, Deichmann, Ralf, Nöth, Ulrike, Hattingen, Elke, Gracien, René-Maxime, Wagner, Marlies, Seiler, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957754/ https://www.ncbi.nlm.nih.gov/pubmed/36851996 http://dx.doi.org/10.1016/j.cccb.2023.100162

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