Long-chain polyunsaturated lipids associated with responsiveness to anti-PD-1 therapy are colocalized with immune infiltrates in the tumor microenvironment

The programmed cell death protein-1 (PD-1) is highly expressed on the surface of antigen-specific exhausted T cells and, upon interaction with its ligand PD-L1, can result in inhibition of the immune response. Anti-PD-1 treatment has been shown to extend survival and result in durable responses in s...

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Detalles Bibliográficos
Autores principales: King, Mary E., Yuan, Robert, Chen, Jeremy, Pradhan, Komal, Sariol, Isabel, Li, Shirley, Chakraborty, Ashish, Ekpenyong, Oscar, Yearley, Jennifer H., Wong, Janica C., Zúñiga, Luis, Tomazela, Daniela, Beaumont, Maribel, Han, Jin-Hwan, Eberlin, Livia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957763/
https://www.ncbi.nlm.nih.gov/pubmed/36642178
http://dx.doi.org/10.1016/j.jbc.2023.102902

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