Identification of MKNK1 and TOP3A as ovarian endometriosis risk-associated genes using integrative genomic analyses and functional experiments

The risk of endometriosis (EM), which is a common complex gynaecological disease, is related to genetic predisposition. However, it is unclear how genetic variants confer the risk of EM. Here, via Sherlock integrative analysis, we combined large-scale genome-wide association studies (GWAS) summary s...

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Detalles Bibliográficos
Autores principales: Huang, Yizhou, Luo, Jie, Zhang, Yue, Zhang, Tao, Fei, Xiangwei, Chen, Liqing, Zhu, Yingfan, Li, Songyue, Zhou, Caiyun, Xu, Kaihong, Ma, Yunlong, Lin, Jun, Zhou, Jianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957794/
https://www.ncbi.nlm.nih.gov/pubmed/36851918
http://dx.doi.org/10.1016/j.csbj.2023.02.001

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