Maltol ameliorates intervertebral disc degeneration through inhibiting PI3K/AKT/NF-κB pathway and regulating NLRP3 inflammasome-mediated pyroptosis

OBJECTIVES: As one of the major causes of low back pain, intervertebral disc degeneration (IDD) has caused a huge problem for humans. Increasing evidence indicates that NLRP3 inflammasome-mediated pyroptosis of NP cells displays an important role in the progression of IDD. Maltol (MA) is a flavoring...

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Detalles Bibliográficos
Autores principales: Gong, Yuhang, Qiu, Jianxing, Jiang, Ting, Li, Ze, Zhang, Weikang, Zheng, Xiaohang, He, Zixuan, Chen, Weifu, Wang, Zhangfu, Feng, Xingbing, Wang, Meizhen, Hong, Zhenghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9957850/
https://www.ncbi.nlm.nih.gov/pubmed/36401729
http://dx.doi.org/10.1007/s10787-022-01098-5

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