Citrullination modulates antigen processing and presentation by revealing cryptic epitopes in rheumatoid arthritis

Cryptic peptides, hidden from the immune system under physiologic conditions, are revealed by changes to MHC class II processing and hypothesized to drive the loss of immune tolerance to self-antigens in autoimmunity. Rheumatoid arthritis (RA) is an autoimmune disease characterized by immune respons...

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Detalles Bibliográficos
Autores principales: Curran, Ashley M., Girgis, Alexander A., Jang, Yura, Crawford, Jonathan D., Thomas, Mekha A., Kawalerski, Ryan, Coller, Jeff, Bingham, Clifton O., Na, Chan Hyun, Darrah, Erika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958131/
https://www.ncbi.nlm.nih.gov/pubmed/36828807
http://dx.doi.org/10.1038/s41467-023-36620-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958131/
https://www.ncbi.nlm.nih.gov/pubmed/36828807
http://dx.doi.org/10.1038/s41467-023-36620-y

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