Deficiency of Parkinson’s Related Protein DJ-1 Alters Cdk5 Signalling and Induces Neuronal Death by Aberrant Cell Cycle Re-entry

ABSTRACT: DJ-1 is a multifunctional protein involved in Parkinson disease (PD) that can act as antioxidant, molecular chaperone, protease, glyoxalase, and transcriptional regulator. However, the exact mechanism by which DJ-1 dysfunction contributes to development of Parkinson’s disease remains elusi...

Descripción completa

Detalles Bibliográficos
Autores principales: López-Grueso, María José, Padilla, Carmen Alicia, Bárcena, José Antonio, Requejo-Aguilar, Raquel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958167/
https://www.ncbi.nlm.nih.gov/pubmed/35182267
http://dx.doi.org/10.1007/s10571-022-01206-7

Ejemplares similares

Ejemplares similares