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Chimeric Hepatitis B core virus-like particles harboring SARS-CoV2 epitope elicit a humoral immune response in mice

BACKGROUND: Virus-like particles are an interesting vector platform for vaccine development. Particularly, Hepatitis B virus core antigen has been used as a promising VLP platform. It is highly expressed in different recombinant expression systems, such as E. coli, and self-assembled in vitro. It ef...

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Detalles Bibliográficos
Autores principales: Sazegari, Sima, Akbarzadeh Niaki, Malihe, Afsharifar, Alireza, Niazi, Ali, Derakhshandeh, Abdollah, Moradi Vahdat, Maryam, Hemmati, Farshad, Eskandari, Mohammad Hadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958315/
https://www.ncbi.nlm.nih.gov/pubmed/36841778
http://dx.doi.org/10.1186/s12934-023-02043-z