Pangenome obtained by long-read sequencing of 11 genomes reveal hidden functional structural variants in pigs

Long-read sequencing (LRS) facilitates both the genome assembly and the discovery of structural variants (SVs). Here, we built a graph-based pig pangenome by incorporating 11 LRS genomes with an average of 94.01% BUSCO completeness score, revealing 206-Mb novel sequences. We discovered 183,352 nonre...

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Detalles Bibliográficos
Autores principales: Jiang, Yi-Fan, Wang, Sheng, Wang, Chong-Long, Xu, Ru-Hai, Wang, Wen-Wen, Jiang, Yao, Wang, Ming-Shan, Jiang, Li, Dai, Li-He, Wang, Jie-Ru, Chu, Xiao-Hong, Zeng, Yong-Qing, Fang, Ling-Zhao, Wu, Dong-Dong, Zhang, Qin, Ding, Xiang-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958381/
https://www.ncbi.nlm.nih.gov/pubmed/36852268
http://dx.doi.org/10.1016/j.isci.2023.106119

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