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Human protothecosis: A case report in northeastern Brazil

We describe a case of extensive human cutaneous protothecosis in the northeastern of Brazil. The diagnosis was made through histopathological examination of skin samples and culturing on Sabouraud dextrose agar, with identification through mass spectrometry. Treatment with itraconazole failed and wa...

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Detalles Bibliográficos
Autores principales: Santos, Daniel Wagner de Castro Lima, Magalhaes Diniz, Yankee Costa, Silva, Raimunda Ribeiro da, Marques, Sirlei Garcia, Bomfim, Maria Rosa Quaresma, de Azevedo, Conceição de Maria Pedrozo e Silva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958387/
https://www.ncbi.nlm.nih.gov/pubmed/36851995
http://dx.doi.org/10.1016/j.mmcr.2023.02.003
Descripción
Sumario:We describe a case of extensive human cutaneous protothecosis in the northeastern of Brazil. The diagnosis was made through histopathological examination of skin samples and culturing on Sabouraud dextrose agar, with identification through mass spectrometry. Treatment with itraconazole failed and was switched to liposomal amphotericin followed by voriconazole with clinical cure. Prothotecosis should be a diagnostic hypothesis when there are skin lesions after trauma, specially in situations of atypical evolution.