Human protothecosis: A case report in northeastern Brazil

We describe a case of extensive human cutaneous protothecosis in the northeastern of Brazil. The diagnosis was made through histopathological examination of skin samples and culturing on Sabouraud dextrose agar, with identification through mass spectrometry. Treatment with itraconazole failed and wa...

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Autores principales: Santos, Daniel Wagner de Castro Lima, Magalhaes Diniz, Yankee Costa, Silva, Raimunda Ribeiro da, Marques, Sirlei Garcia, Bomfim, Maria Rosa Quaresma, de Azevedo, Conceição de Maria Pedrozo e Silva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958387/
https://www.ncbi.nlm.nih.gov/pubmed/36851995
http://dx.doi.org/10.1016/j.mmcr.2023.02.003
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author Santos, Daniel Wagner de Castro Lima
Magalhaes Diniz, Yankee Costa
Silva, Raimunda Ribeiro da
Marques, Sirlei Garcia
Bomfim, Maria Rosa Quaresma
de Azevedo, Conceição de Maria Pedrozo e Silva
author_facet Santos, Daniel Wagner de Castro Lima
Magalhaes Diniz, Yankee Costa
Silva, Raimunda Ribeiro da
Marques, Sirlei Garcia
Bomfim, Maria Rosa Quaresma
de Azevedo, Conceição de Maria Pedrozo e Silva
author_sort Santos, Daniel Wagner de Castro Lima
collection PubMed
description We describe a case of extensive human cutaneous protothecosis in the northeastern of Brazil. The diagnosis was made through histopathological examination of skin samples and culturing on Sabouraud dextrose agar, with identification through mass spectrometry. Treatment with itraconazole failed and was switched to liposomal amphotericin followed by voriconazole with clinical cure. Prothotecosis should be a diagnostic hypothesis when there are skin lesions after trauma, specially in situations of atypical evolution.
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spelling pubmed-99583872023-02-26 Human protothecosis: A case report in northeastern Brazil Santos, Daniel Wagner de Castro Lima Magalhaes Diniz, Yankee Costa Silva, Raimunda Ribeiro da Marques, Sirlei Garcia Bomfim, Maria Rosa Quaresma de Azevedo, Conceição de Maria Pedrozo e Silva Med Mycol Case Rep Case Report We describe a case of extensive human cutaneous protothecosis in the northeastern of Brazil. The diagnosis was made through histopathological examination of skin samples and culturing on Sabouraud dextrose agar, with identification through mass spectrometry. Treatment with itraconazole failed and was switched to liposomal amphotericin followed by voriconazole with clinical cure. Prothotecosis should be a diagnostic hypothesis when there are skin lesions after trauma, specially in situations of atypical evolution. Elsevier 2023-02-14 /pmc/articles/PMC9958387/ /pubmed/36851995 http://dx.doi.org/10.1016/j.mmcr.2023.02.003 Text en © 2023 Published by Elsevier B.V. on behalf of International Society for Human and Animal Mycology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Santos, Daniel Wagner de Castro Lima
Magalhaes Diniz, Yankee Costa
Silva, Raimunda Ribeiro da
Marques, Sirlei Garcia
Bomfim, Maria Rosa Quaresma
de Azevedo, Conceição de Maria Pedrozo e Silva
Human protothecosis: A case report in northeastern Brazil
title Human protothecosis: A case report in northeastern Brazil
title_full Human protothecosis: A case report in northeastern Brazil
title_fullStr Human protothecosis: A case report in northeastern Brazil
title_full_unstemmed Human protothecosis: A case report in northeastern Brazil
title_short Human protothecosis: A case report in northeastern Brazil
title_sort human protothecosis: a case report in northeastern brazil
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958387/
https://www.ncbi.nlm.nih.gov/pubmed/36851995
http://dx.doi.org/10.1016/j.mmcr.2023.02.003
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