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Decreased expression of mitochondrial aminoacyl-tRNA synthetases causes downregulation of OXPHOS subunits in type 2 diabetic muscle

Type 2 diabetes mellitus (T2D) affects millions of people worldwide and is one of the leading causes of morbidity and mortality. The skeletal muscle (SKM) is one of the most important tissues involved in maintaining glucose homeostasis and substrate oxidation, and it undergoes insulin resistance in...

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Detalles Bibliográficos
Autores principales: López-Soldado, Iliana, Torres, Adrian Gabriel, Ventura, Raúl, Martínez-Ruiz, Inma, Díaz-Ramos, Angels, Planet, Evarist, Cooper, Diane, Pazderska, Agnieszka, Wanic, Krzysztof, O'Hanlon, Declan, O'Gorman, Donal J., Carbonell, Teresa, de Pouplana, Lluís Ribas, Nolan, John J., Zorzano, Antonio, Hernández-Alvarez, María Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958393/
https://www.ncbi.nlm.nih.gov/pubmed/36796135
http://dx.doi.org/10.1016/j.redox.2023.102630