Stiffness-tuned and ROS-sensitive hydrogel incorporating complement C5a receptor antagonist modulates antibacterial activity of macrophages for periodontitis treatment

Periodontitis is admittedly a microbe-driven intractable infectious disease, in which Porphyromonas gingivalis (Pg) plays a keystone role. Pg can selectively impair the antimicrobial responses of periodontal resident macrophages including their phagocytic and bactericidal activity without interferin...

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Detalles Bibliográficos
Autores principales: Gan, Ziqi, Xiao, Zecong, Zhang, Zhen, Li, Yang, Liu, Chao, Chen, Xin, Liu, Yuanbo, Wu, Dongle, Liu, Chufeng, Shuai, Xintao, Cao, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958411/
https://www.ncbi.nlm.nih.gov/pubmed/36852104
http://dx.doi.org/10.1016/j.bioactmat.2023.01.011

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