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Cystathionine-γ-lyase overexpression modulates oxidized nicotinamide adenine dinucleotide biosynthesis and enhances neovascularization

OBJECTIVE: Hydrogen sulfide is a proangiogenic gas produced primarily by the transsulfuration enzyme cystathionine-γ-lyase (CGL). CGL-dependent hydrogen sulfide production is required for neovascularization in models of peripheral arterial disease. However, the benefits of increasing endogenous CGL...

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Detalles Bibliográficos
Autores principales:	Kiesworo, Kevin, MacArthur, Michael R., Kip, Peter, Agius, Thomas, Macabrey, Diane, Lambelet, Martine, Hamard, Lauriane, Ozaki, C.-Keith, Mitchell, James R., Déglise, Sébastien, Mitchell, Sarah J., Allagnat, Florent, Longchamp, Alban
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958478/ https://www.ncbi.nlm.nih.gov/pubmed/36852171 http://dx.doi.org/10.1016/j.jvssci.2022.11.003

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