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High-throughput screening for myelination promoting compounds using human stem cell-derived oligodendrocyte progenitor cells

Promoting myelination capacity of endogenous oligodendrocyte precursor cells (OPCs) is a promising therapeutic approach for CNS demyelinating disorders such as Multiple Sclerosis (MS). To aid in the discovery of myelination-promoting compounds, we generated a genome-engineered human pluripotent stem...

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Detalles Bibliográficos
Autores principales:	Li, Weifeng, Berlinicke, Cynthia, Huang, Yinyin, Giera, Stefanie, McGrath, Anna G., Fang, Weixiang, Chen, Chaoran, Takaesu, Felipe, Chang, Xiaoli, Duan, Yukan, Kumar, Dinesh, Chang, Calvin, Mao, Hai-Quan, Sheng, Guoqing, Dodge, James C., Ji, Hongkai, Madden, Stephen, Zack, Donald J., Chamling, Xitiz
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958491/ https://www.ncbi.nlm.nih.gov/pubmed/36852281 http://dx.doi.org/10.1016/j.isci.2023.106156

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