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Nasal Tumor Vaccination Protects against Lung Tumor Development by Induction of Resident Effector and Memory Anti-Tumor Immune Responses

Lung metastasis is a leading cause of cancer-related deaths. Here, we show that intranasal delivery of our engineered CpG-coated tumor antigen (Tag)-encapsulated nanoparticles (NPs)—nasal nano-vaccine—significantly reduced lung colonization by intravenous challenge of an extra-pulmonary tumor. Prote...

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Detalles Bibliográficos
Autores principales:	Donkor, Michael, Choe, Jamie, Reid, Danielle Marie, Quinn, Byron, Pulse, Mark, Ranjan, Amalendu, Chaudhary, Pankaj, Jones, Harlan P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958580/ https://www.ncbi.nlm.nih.gov/pubmed/36839766 http://dx.doi.org/10.3390/pharmaceutics15020445

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