Cargando…
Properties and Bioapplications of Amphiphilic Janus Dendrimers: A Review
Amphiphilic Janus dendrimers are arrangements containing both hydrophilic and hydrophobic units, capable of forming ordered aggregates by intermolecular noncovalent interactions between the dendrimer units. Compared to conventional dendrimers, these molecular self-assemblies possess particular and e...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958631/ https://www.ncbi.nlm.nih.gov/pubmed/36839911 http://dx.doi.org/10.3390/pharmaceutics15020589 |
_version_ | 1784895072029900800 |
---|---|
author | Căta, Adina Ienașcu, Ioana Maria Carmen Ştefănuț, Mariana Nela Roșu, Dan Pop, Oana-Raluca |
author_facet | Căta, Adina Ienașcu, Ioana Maria Carmen Ştefănuț, Mariana Nela Roșu, Dan Pop, Oana-Raluca |
author_sort | Căta, Adina |
collection | PubMed |
description | Amphiphilic Janus dendrimers are arrangements containing both hydrophilic and hydrophobic units, capable of forming ordered aggregates by intermolecular noncovalent interactions between the dendrimer units. Compared to conventional dendrimers, these molecular self-assemblies possess particular and effective attributes i.e., the presence of different terminal groups, essential to design new elaborated materials. The present review will focus on the pharmaceutical and biomedical application of amphiphilic Janus dendrimers. Important information for the development of novel optimized pharmaceutical formulations, such as structural classification, synthetic pathways, properties and applications, will offer the complete characterization of this type of Janus dendrimers. This work will constitute an up-to-date background for dendrimer specialists involved in designing amphiphilic Janus dendrimer-based nanomaterials for future innovations in this promising field. |
format | Online Article Text |
id | pubmed-9958631 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99586312023-02-26 Properties and Bioapplications of Amphiphilic Janus Dendrimers: A Review Căta, Adina Ienașcu, Ioana Maria Carmen Ştefănuț, Mariana Nela Roșu, Dan Pop, Oana-Raluca Pharmaceutics Review Amphiphilic Janus dendrimers are arrangements containing both hydrophilic and hydrophobic units, capable of forming ordered aggregates by intermolecular noncovalent interactions between the dendrimer units. Compared to conventional dendrimers, these molecular self-assemblies possess particular and effective attributes i.e., the presence of different terminal groups, essential to design new elaborated materials. The present review will focus on the pharmaceutical and biomedical application of amphiphilic Janus dendrimers. Important information for the development of novel optimized pharmaceutical formulations, such as structural classification, synthetic pathways, properties and applications, will offer the complete characterization of this type of Janus dendrimers. This work will constitute an up-to-date background for dendrimer specialists involved in designing amphiphilic Janus dendrimer-based nanomaterials for future innovations in this promising field. MDPI 2023-02-09 /pmc/articles/PMC9958631/ /pubmed/36839911 http://dx.doi.org/10.3390/pharmaceutics15020589 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Căta, Adina Ienașcu, Ioana Maria Carmen Ştefănuț, Mariana Nela Roșu, Dan Pop, Oana-Raluca Properties and Bioapplications of Amphiphilic Janus Dendrimers: A Review |
title | Properties and Bioapplications of Amphiphilic Janus Dendrimers: A Review |
title_full | Properties and Bioapplications of Amphiphilic Janus Dendrimers: A Review |
title_fullStr | Properties and Bioapplications of Amphiphilic Janus Dendrimers: A Review |
title_full_unstemmed | Properties and Bioapplications of Amphiphilic Janus Dendrimers: A Review |
title_short | Properties and Bioapplications of Amphiphilic Janus Dendrimers: A Review |
title_sort | properties and bioapplications of amphiphilic janus dendrimers: a review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958631/ https://www.ncbi.nlm.nih.gov/pubmed/36839911 http://dx.doi.org/10.3390/pharmaceutics15020589 |
work_keys_str_mv | AT cataadina propertiesandbioapplicationsofamphiphilicjanusdendrimersareview AT ienascuioanamariacarmen propertiesandbioapplicationsofamphiphilicjanusdendrimersareview AT stefanutmariananela propertiesandbioapplicationsofamphiphilicjanusdendrimersareview AT rosudan propertiesandbioapplicationsofamphiphilicjanusdendrimersareview AT popoanaraluca propertiesandbioapplicationsofamphiphilicjanusdendrimersareview |