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Migraine and Hormonal Contraception in Gynecological Outpatient Care—Cross-Sectional Study among Practicing Gynecologists in Germany

Hormonal contraception (HC) can influence the migraine burden and should be considered in the comprehensive management of women with migraine. In this study, we aim to investigate the influence of migraine and migraine aura on the prescribing behavior of combined oral contraception (COC) and progest...

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Autores principales: Fitzek, Mira P., Storch, Elisabeth, Overeem, Lucas H., Kull, Pia, Terhart, Maria, Lange, Kristin S., Reuter, Uwe, Raffaelli, Bianca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958685/
https://www.ncbi.nlm.nih.gov/pubmed/36835967
http://dx.doi.org/10.3390/jcm12041434
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author Fitzek, Mira P.
Storch, Elisabeth
Overeem, Lucas H.
Kull, Pia
Terhart, Maria
Lange, Kristin S.
Reuter, Uwe
Raffaelli, Bianca
author_facet Fitzek, Mira P.
Storch, Elisabeth
Overeem, Lucas H.
Kull, Pia
Terhart, Maria
Lange, Kristin S.
Reuter, Uwe
Raffaelli, Bianca
author_sort Fitzek, Mira P.
collection PubMed
description Hormonal contraception (HC) can influence the migraine burden and should be considered in the comprehensive management of women with migraine. In this study, we aim to investigate the influence of migraine and migraine aura on the prescribing behavior of combined oral contraception (COC) and progestogen monotherapy (PM) in gynecological outpatient care. From October 2021 to March 2022, we performed an observational, cross-sectional study using a self-administered online-based survey. The questionnaire was distributed by mail and e-mail among 11,834 practicing gynecologists in Germany using the publicly available contact information. A total of 851 gynecologists responded to the questionnaire, of whom 12% never prescribe COC in the presence of migraine. Further 75% prescribe COC depending on the presence of limiting factors such as cardiovascular risk factors and comorbidities. When deciding to start PM, migraine appears to be less relevant, as 82% prescribe PM without restrictions. In the presence of aura, 90% of gynecologists do not prescribe COC at all, while PM is prescribed in 53% without restrictions. Almost all gynecologists reported to be actively involved in migraine therapy by having already initiated (80%), discontinued (96%), or changed (99%) HC due to migraine. Our results reveal that participating gynecologists actively consider migraine and migraine aura before and while prescribing HC. Gynecologists appear cautious in prescribing HC in patients with migraine aura.
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spelling pubmed-99586852023-02-26 Migraine and Hormonal Contraception in Gynecological Outpatient Care—Cross-Sectional Study among Practicing Gynecologists in Germany Fitzek, Mira P. Storch, Elisabeth Overeem, Lucas H. Kull, Pia Terhart, Maria Lange, Kristin S. Reuter, Uwe Raffaelli, Bianca J Clin Med Article Hormonal contraception (HC) can influence the migraine burden and should be considered in the comprehensive management of women with migraine. In this study, we aim to investigate the influence of migraine and migraine aura on the prescribing behavior of combined oral contraception (COC) and progestogen monotherapy (PM) in gynecological outpatient care. From October 2021 to March 2022, we performed an observational, cross-sectional study using a self-administered online-based survey. The questionnaire was distributed by mail and e-mail among 11,834 practicing gynecologists in Germany using the publicly available contact information. A total of 851 gynecologists responded to the questionnaire, of whom 12% never prescribe COC in the presence of migraine. Further 75% prescribe COC depending on the presence of limiting factors such as cardiovascular risk factors and comorbidities. When deciding to start PM, migraine appears to be less relevant, as 82% prescribe PM without restrictions. In the presence of aura, 90% of gynecologists do not prescribe COC at all, while PM is prescribed in 53% without restrictions. Almost all gynecologists reported to be actively involved in migraine therapy by having already initiated (80%), discontinued (96%), or changed (99%) HC due to migraine. Our results reveal that participating gynecologists actively consider migraine and migraine aura before and while prescribing HC. Gynecologists appear cautious in prescribing HC in patients with migraine aura. MDPI 2023-02-10 /pmc/articles/PMC9958685/ /pubmed/36835967 http://dx.doi.org/10.3390/jcm12041434 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Fitzek, Mira P.
Storch, Elisabeth
Overeem, Lucas H.
Kull, Pia
Terhart, Maria
Lange, Kristin S.
Reuter, Uwe
Raffaelli, Bianca
Migraine and Hormonal Contraception in Gynecological Outpatient Care—Cross-Sectional Study among Practicing Gynecologists in Germany
title Migraine and Hormonal Contraception in Gynecological Outpatient Care—Cross-Sectional Study among Practicing Gynecologists in Germany
title_full Migraine and Hormonal Contraception in Gynecological Outpatient Care—Cross-Sectional Study among Practicing Gynecologists in Germany
title_fullStr Migraine and Hormonal Contraception in Gynecological Outpatient Care—Cross-Sectional Study among Practicing Gynecologists in Germany
title_full_unstemmed Migraine and Hormonal Contraception in Gynecological Outpatient Care—Cross-Sectional Study among Practicing Gynecologists in Germany
title_short Migraine and Hormonal Contraception in Gynecological Outpatient Care—Cross-Sectional Study among Practicing Gynecologists in Germany
title_sort migraine and hormonal contraception in gynecological outpatient care—cross-sectional study among practicing gynecologists in germany
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958685/
https://www.ncbi.nlm.nih.gov/pubmed/36835967
http://dx.doi.org/10.3390/jcm12041434
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