Cargando…

Quercetin and Its Derivative Counteract Palmitate-Dependent Lipotoxicity by Inhibiting Oxidative Stress and Inflammation in Cardiomyocytes

Cardiac lipotoxicity plays an important role in the pathogenesis of obesity-related cardiovascular disease. The flavonoid quercetin (QUE), a nutraceutical compound that is abundant in the “Mediterranean diet”, has been shown to be a potential therapeutic agent in cardiac and metabolic diseases. Here...

Descripción completa

Detalles Bibliográficos
Autores principales:	Granieri, Maria Concetta, Rocca, Carmine, De Bartolo, Anna, Nettore, Immacolata Cristina, Rago, Vittoria, Romeo, Naomi, Ceramella, Jessica, Mariconda, Annaluisa, Macchia, Paolo Emidio, Ungaro, Paola, Sinicropi, Maria Stefania, Angelone, Tommaso
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958705/ https://www.ncbi.nlm.nih.gov/pubmed/36834186 http://dx.doi.org/10.3390/ijerph20043492

Ejemplares similares

Palmitate-Induced Cardiac Lipotoxicity Is Relieved by the Redox-Active Motif of SELENOT through Improving Mitochondrial Function and Regulating Metabolic State
por: Rocca, Carmine, et al.
Publicado: (2023)

Sunshine vitamin and thyroid
por: Nettore, Immacolata Cristina, et al.
Publicado: (2017)

Epigenetic Mechanisms of Endocrine-Disrupting Chemicals in Obesity
por: Nettore, Immacolata Cristina, et al.
Publicado: (2021)

Biological Activities of Ruthenium NHC Complexes: An Update
por: Catalano, Alessia, et al.
Publicado: (2023)

Nutritional and Environmental Factors in Thyroid Carcinogenesis
por: Nettore, Immacolata Cristina, et al.
Publicado: (2018)

Obesity and Thyroid Cancer Risk: An Update
por: Franchini, Fabiana, et al.
Publicado: (2022)

Epigenome Modulation Induced by Ketogenic Diets
por: Ungaro, Paola, et al.
Publicado: (2022)

Association between Dietary Habits and Severity of Symptoms in Premenstrual Syndrome
por: Quaglia, Cinzia, et al.
Publicado: (2023)

Is the Way to Fight Cancer Paved with Gold? Metal-Based Carbene Complexes with Multiple and Fascinating Biological Features
por: Iacopetta, Domenico, et al.
Publicado: (2020)

COVID-19 at a Glance: An Up-to-Date Overview on Variants, Drug Design and Therapies
por: Iacopetta, Domenico, et al.
Publicado: (2022)

Novel Au Carbene Complexes as Promising Multi-Target Agents in Breast Cancer Treatment
por: Ceramella, Jessica, et al.
Publicado: (2022)

Triclosan: A Small Molecule with Controversial Roles
por: Sinicropi, Maria Stefania, et al.
Publicado: (2022)

Metal Complexes with Schiff Bases: Data Collection and Recent Studies on Biological Activities
por: Sinicropi, Maria Stefania, et al.
Publicado: (2022)

The Antioxidant Selenoprotein T Mimetic, PSELT, Induces Preconditioning-like Myocardial Protection by Relieving Endoplasmic-Reticulum Stress
por: Rocca, Carmine, et al.
Publicado: (2022)

Drugs for COVID-19: An Update
por: Ceramella, Jessica, et al.
Publicado: (2022)

Synthesis of Novel N-Heterocyclic Carbene-Ruthenium (II) Complexes, “Precious” Tools with Antibacterial, Anticancer and Antioxidant Properties
por: Ceramella, Jessica, et al.
Publicado: (2023)

Bis-Thiourea Quaternary Ammonium Salts as Potential Agents against Bacterial Strains from Food and Environmental Matrices
por: Bonomo, Maria Grazia, et al.
Publicado: (2021)

Thidiazuron: New Trends and Future Perspectives to Fight Xylella fastidiosa in Olive Trees
por: Catalano, Alessia, et al.
Publicado: (2022)

5,8-Dimethyl-9H-carbazole Derivatives Blocking hTopo I Activity and Actin Dynamics
por: Ceramella, Jessica, et al.
Publicado: (2023)

Palmitic Acid Induced a Long-Lasting Lipotoxic Insult in Human Retinal Pigment Epithelial Cells, which Is Partially Counteracted by TRAIL
por: Sergi, Domenico, et al.
Publicado: (2022)

Lipotoxicity of Palmitic Acid on Neural Progenitor Cells and Hippocampal Neurogenesis
por: Park, Hee Ra, et al.
Publicado: (2011)

Lysosomal Ca(2+) as a mediator of palmitate-induced lipotoxicity
por: Oh, Soo-Jin, et al.
Publicado: (2023)

Influences of Age, Sex and Smoking Habit on Flavor Recognition in Healthy Population
por: Nettore, Immacolata Cristina, et al.
Publicado: (2020)

Newly Synthesized Imino-Derivatives Analogues of Resveratrol Exert Inhibitory Effects in Breast Tumor Cells
por: Iacopetta, Domenico, et al.
Publicado: (2020)

Palmitic Acid Lipotoxicity in Microglia Cells Is Ameliorated by Unsaturated Fatty Acids
por: Urso, C.J., et al.
Publicado: (2021)

Increased glycolysis is an early consequence of palmitate lipotoxicity mediated by redox signaling
por: Kakimoto, Pamela A., et al.
Publicado: (2021)

N‐Heterocyclic Carbene (NHC) Silver Complexes as Versatile Chemotherapeutic Agents Targeting Human Topoisomerases and Actin
por: Mariconda, Annaluisa, et al.
Publicado: (2022)

Quantitative but not qualitative flavor recognition impairments in COVID-19 patients
por: Nettore, Immacolata Cristina, et al.
Publicado: (2021)

Protection of palmitic acid-mediated lipotoxicity by arachidonic acid via channeling of palmitic acid into triglycerides in C2C12
por: Cheon, Hyae Gyeong, et al.
Publicado: (2014)

Role of CD36 in Palmitic Acid Lipotoxicity in Neuro-2a Neuroblastoma Cells
por: Urso, C. J., et al.
Publicado: (2021)

Palmitate lipotoxicity is closely associated with the fatty acid-albumin complexes in BV-2 microglia
por: Yang, Yanzhuo, et al.
Publicado: (2023)

ER calcium release promotes mitochondrial dysfunction and hepatic cell lipotoxicity in response to palmitate overload
por: Egnatchik, Robert A., et al.
Publicado: (2014)

The TLR4‐IRE1α pathway activation contributes to palmitate‐elicited lipotoxicity in hepatocytes
por: Shen, Chen, et al.
Publicado: (2018)

Cytoprotective Effect of Hispidin against Palmitate-Induced Lipotoxicity in C2C12 Myotubes
por: Park, Jun Myoung, et al.
Publicado: (2015)

Oleic acid ameliorates palmitic acid induced hepatocellular lipotoxicity by inhibition of ER stress and pyroptosis
por: Zeng, Xin, et al.
Publicado: (2020)

Protopanaxadiol ameliorates palmitate-induced lipotoxicity and pancreatic β-cell dysfunction in INS-1 cells
por: Lee, Dahae, et al.
Publicado: (2023)

Mitochondrial Determinants of Anti-Cancer Drug-Induced Cardiotoxicity
por: Rocca, Carmine, et al.
Publicado: (2022)

Preliminary results demonstrating the impact of Mediterranean diet on bone health
por: Savanelli, Maria Cristina, et al.
Publicado: (2017)

Palmitate-induced lipotoxicity is crucial for the pathogenesis of nonalcoholic fatty liver disease in cooperation with gut-derived endotoxin
por: Ogawa, Yuji, et al.
Publicado: (2018)

Palmitate-induced lipotoxicity alters acetylation of multiple proteins in clonal β cells and human pancreatic islets
por: Ciregia, Federica, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_3fe80um7qfhlm8e68ln4v6fsfp