A Novel 5-Chloro-N-phenyl-1H-indole-2-carboxamide Derivative as Brain-Type Glycogen Phosphorylase Inhibitor: Validation of Target PYGB

Brain-type glycogen phosphorylase (PYGB) inhibitors are recognized as prospective drugs for treating ischemic brain injury. We previously reported compound 1 as a novel glycogen phosphorylase inhibitor with brain-protective properties. In this study, we validated whether PYGB could be used as the th...

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Detalles Bibliográficos
Autores principales: Huang, Yatao, Li, Shuai, Wang, Youde, Yan, Zhiwei, Guo, Yachun, Zhang, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958726/
https://www.ncbi.nlm.nih.gov/pubmed/36838691
http://dx.doi.org/10.3390/molecules28041697

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958726/
https://www.ncbi.nlm.nih.gov/pubmed/36838691
http://dx.doi.org/10.3390/molecules28041697

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