Immunothrombosis: Molecular Aspects and New Therapeutic Perspectives

Thromboinflammation or immunothrombosis is a concept that explains the existing link between coagulation and inflammatory response present in many situations, such as sepsis, venous thromboembolism, or COVID-19 associated coagulopathy. The purpose of this review is to provide an overview of the curr...

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Detalles Bibliográficos
Autores principales: Marcos-Jubilar, María, Lecumberri, Ramón, Páramo, José A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958829/
https://www.ncbi.nlm.nih.gov/pubmed/36835934
http://dx.doi.org/10.3390/jcm12041399
Descripción
Sumario:Thromboinflammation or immunothrombosis is a concept that explains the existing link between coagulation and inflammatory response present in many situations, such as sepsis, venous thromboembolism, or COVID-19 associated coagulopathy. The purpose of this review is to provide an overview of the current data regarding the mechanisms involved in immunothrombosis in order to understand the new therapeutic strategies focused in reducing thrombotic risk by controlling the inflammation.

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