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Regulation of Human Endogenous Metabolites by Drug Transporters and Drug Metabolizing Enzymes: An Analysis of Targeted SNP-Metabolite Associations

Drug transporters and drug-metabolizing enzymes are primarily known for their role in the absorption, distribution, metabolism, and excretion (ADME) of small molecule drugs, but they also play a key role in handling endogenous metabolites. Recent cross-tissue co-expression network analyses have reve...

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Detalles Bibliográficos
Autores principales: Granados, Jeffry C., Watrous, Jeramie D., Long, Tao, Rosenthal, Sara Brin, Cheng, Susan, Jain, Mohit, Nigam, Sanjay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958903/
https://www.ncbi.nlm.nih.gov/pubmed/36837791
http://dx.doi.org/10.3390/metabo13020171