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Scaling Up of Steric Exclusion Membrane Chromatography for Lentiviral Vector Purification

Lentiviral vectors (LVs) are widely used in clinical trials of gene and cell therapy. Low LV stability incentivizes constant development and the improvement of gentle process steps. Steric exclusion chromatography (SXC) has gained interest in the field of virus purification but scaling up has not ye...

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Detalles Bibliográficos
Autores principales: Labisch, Jennifer Julia, Paul, Richard, Wiese, G. Philip, Pflanz, Karl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9958935/
https://www.ncbi.nlm.nih.gov/pubmed/36837652
http://dx.doi.org/10.3390/membranes13020149